# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4340227 | F | Antiproliferative activity against human KOPTK1 cells harboring activating Notch1 gene mutations assessed as reduction in cell viability at 2.5 uM incubated for 36 hrs by MTS assay | Homo sapiens | 6 | ALA4339229 | cell-based format | Scientific Literature | |
2. | ALA4340230 | F | Antiproliferative activity against human KOPTK1 cells harboring activating Notch1 gene mutations assessed as reduction in cell viability incubated for 36 hrs by MTS assay | Homo sapiens | 6 | ALA4339229 | cell-based format | Scientific Literature | |
3. | ALA4340231 | F | Induction of cell death in human KOPTK1 cells harboring activating Notch1 gene mutations assessed as increase in p27kip protein expression at 2.5 uM incubated for 36 hrs by Western blot analysis | Homo sapiens | 5 | ALA4339229 | cell-based format | Scientific Literature | |
4. | ALA4340232 | F | Induction of cell death in human KOPTK1 cells harboring activating Notch1 gene mutations assessed as increase in cleaved PARP protein expression at 2.5 uM incubated for 36 hrs by Western blot analysis | Homo sapiens | 5 | ALA4339229 | cell-based format | Scientific Literature | |
5. | ALA4403357 | F | Cytotoxicity against human KOPTK1 cells assessed as reduction in cell viability | Homo sapiens | 1 | ALA4402527 | cell-based format | Scientific Literature | |
6. | ALA4403361 | F | Anti-tumor activity against human KOPTK1 cells xenografted in invivo animal model assessed as reduction in tumor growth at 10 mg/kg, ip relative to control | Homo sapiens | 1 | ALA4402527 | organism-based format | Scientific Literature | |
7. | ALA5038535 | F | Anticancer activity against human KOPT-K1 cells assessed as reduction of cell viability at 280 nM relative to control | Homo sapiens | 1 | ALA5036383 | cell-based format | Scientific Literature | |
8. | ALA5038540 | F | Anticancer activity against human KOPT-K1 cells assessed as reduction of cell viability at 70 nM relative to control | Homo sapiens | 1 | ALA5036383 | cell-based format | Scientific Literature | |
9. | ALA5038545 | F | Anticancer activity against human KOPT-K1 cells assessed as reduction of cell viability at 140 nM relative to control | Homo sapiens | 1 | ALA5036383 | cell-based format | Scientific Literature | |
10. | ALA5226023 | F | Cytotoxicity against human KOPT-K1 cells incubated for 24 hrs by Celltiter-Glo assay | Homo sapiens | 5 | ALA5223179 | cell-based format | Scientific Literature | |
11. | ALA5226024 | F | Cytotoxicity against human KOPT-K1 cells incubated for 72 hrs by Celltiter-Glo assay | Homo sapiens | 7 | ALA5223179 | cell-based format | Scientific Literature | |
12. | ALA5260485 | F | Cytotoxicity against human KOPT-K1 cells assessed as cell growth inhibition measured after 48 hrs by Celltiter-Glo luminescence assay | Homo sapiens | 2 | ALA5257149 | cell-based format | Scientific Literature | |
13. | ALA5260499 | F | Cytotoxicity against human KOPT-K1 cells assessed as cell growth inhibition measured after 18 hrs followed by compound washout by Celltiter-Glo luminescence assay | Homo sapiens | 1 | ALA5257149 | cell-based format | Scientific Literature | |
14. | ALA5260501 | F | Cytotoxicity against human KOPT-K1 cells assessed as cell growth inhibition measured after 18 hrs by Celltiter-Glo luminescence assay | Homo sapiens | 1 | ALA5257149 | cell-based format | Scientific Literature |