# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4388072 | ADME | Cytotoxicity against mouse MIN6 cells assessed as reduction in cell viability up to 200 uM incubated for 24 hrs by MTT assay | Mus musculus | 16 | ALA4387705 | cell-based format | Scientific Literature | |
2. | ALA4388073 | ADME | Cytotoxicity against mouse MIN6 cells assessed as cell viability at 400 uM incubated for 24 hrs by MTT assay | Mus musculus | 16 | ALA4387705 | cell-based format | Scientific Literature | |
3. | ALA4388074 | Functional | Antidiabetic activity in mouse MIN6 cells after 35 passages assessed as increase in insulin secretion at 100 uM in presence of 25 mM glucose by ELISA relative to control | Mus musculus | 17 | ALA4387705 | cell-based format | Scientific Literature | |
4. | ALA4388075 | Functional | Antidiabetic activity in mouse MIN6 cells after 83 passages assessed as increase in insulin secretion at 100 uM in presence of 25 mM glucose by ELISA relative to control | Mus musculus | 17 | ALA4387705 | cell-based format | Scientific Literature | |
5. | ALA4388076 | Functional | Antidiabetic activity in mouse MIN6 cells after 35 passages assessed as increase in insulin secretion incubated for 48 hrs presence of 1 mM glucose by ELISA | Mus musculus | 3 | ALA4387705 | cell-based format | Scientific Literature | |
6. | ALA4388077 | Functional | Antidiabetic activity in mouse MIN6 cells after 35 passages assessed as increase in insulin secretion incubated for 48 hrs presence of 25 mM glucose by ELISA | Mus musculus | 3 | ALA4387705 | cell-based format | Scientific Literature | |
7. | ALA4388078 | Functional | Antidiabetic activity in mouse MIN6 cells after 83 passages assessed as increase in insulin secretion incubated for 48 hrs presence of 1 mM glucose by ELISA | Mus musculus | 3 | ALA4387705 | cell-based format | Scientific Literature | |
8. | ALA4388079 | Functional | Antidiabetic activity in mouse MIN6 cells after 83 passages assessed as increase in insulin secretion incubated for 48 hrs presence of 25 mM glucose by ELISA | Mus musculus | 2 | ALA4387705 | cell-based format | Scientific Literature | |
9. | ALA4388117 | ADME | Effect on cell morphology in mouse MIN6 cells assessed as cell viability up to 400 uM incubated for 24 hrs | Mus musculus | 16 | ALA4387705 | cell-based format | Scientific Literature | |
10. | ALA3294319 | Functional | Insulinotropic effect in mouse MIN6 cells in presence of 25 mM glucose | Mus musculus | 1 | ALA3286210 | cell-based format | Scientific Literature | |
11. | ALA1943346 | Functional | Induction of insulin secretion in mouse MIN6 cells | Mus musculus | 1 | ALA1938292 | cell-based format | Scientific Literature | |
12. | ALA3243404 | Functional | Increase in 11 mM glucose-stimulated insulin secretion in mouse MIN6 cells measured for 1 hr by ELISA | Mus musculus | 1 | ALA3232870 | cell-based format | Scientific Literature | |
13. | ALA2014158 | Functional | Induction of insulin secretion in mouse MIN6 cells | Mus musculus | 3 | ALA2010799 | cell-based format | Scientific Literature | |
14. | ALA2318452 | Functional | Induction of insulin secretion in mouse MIN6 cells | Mus musculus | 1 | ALA2311350 | cell-based format | Scientific Literature | |
15. | ALA3116899 | Functional | Inhibition of palmitate-induced apoptosis in mouse MIN6 cells assessed as reduction of apoptotic cells at 10 nM preincubated for 24 hrs followed by palmitate challenge measured after 1 hr by Hoechst 33342 staining-based microscopic analysis | Mus musculus | 2 | ALA3112516 | cell-based format | Scientific Literature | |
16. | ALA3116900 | Functional | Inhibition of H202-induced apoptosis in mouse MIN6 cells assessed as change in nuclear fragmentation at 10 nM preincubated for 24 hrs followed by H202 challenge measured after 1 hr by Hoechst 33342 staining-based microscopic analysis | Mus musculus | 2 | ALA3112516 | cell-based format | Scientific Literature | |
17. | ALA3997100 | Functional | Induction of glucose-stimulated insulin secretion in mouse MIN6 cells after 2 hrs by ELISA | Mus musculus | 23 | ALA3994643 | cell-based format | Scientific Literature | |
18. | ALA4267597 | ADME | Effect on 2.5 mM glucose-induced insulin secretion in mouse MIN6 cells at 10 uM measured after 2 hrs by ELISA | Mus musculus | 4 | ALA4265918 | cell-based format | Scientific Literature | |
19. | ALA4345512 | Functional | Inhibition of heparanase (unknown origin) assessed as reduction in ROS production in mouse MIN6 cells co-incubated with heparanase-producing CHO cells at 15 uM incubated for 24 hrs by mitochondrial ROS probe staining based fluorescence microscopic method | Mus musculus | 1 | ALA4342500 | cell-based format | Scientific Literature | |
20. | ALA4345513 | Functional | Inhibition of ROS production in mouse MIN6 cells at 15 uM incubated for 24 hrs by mitochondrial ROS probe staining based fluorescence microscopic method | Mus musculus | 1 | ALA4342500 | cell-based format | Scientific Literature |