# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4411919 | Functional | Antiproliferative activity against human MR49F cells after 3 days followed by compound wash and measured after 6 days by SRB assay | Homo sapiens | 35 | ALA4411271 | cell-based format | Scientific Literature | |
2. | ALA4411932 | Functional | Antiproliferative activity against human MR49F cells after 3 days followed by compound wash and measured after 6 days by CellTiter-Glo assay | Homo sapiens | 3 | ALA4411271 | cell-based format | Scientific Literature | |
3. | ALA4411933 | Functional | Antiproliferative activity against human MR49F cells assessed as inhibition of cell growth at 3 uM after 3 days followed by compound wash and measured after 6 days by CellTiter-Glo assay relative to control | Homo sapiens | 1 | ALA4411271 | cell-based format | Scientific Literature | |
4. | ALA4411934 | Functional | Antiproliferative activity against human MR49F cells assessed as inhibition of cell growth at 10 uM after 3 days followed by compound wash and measured after 6 days by CellTiter-Glo assay relative to control | Homo sapiens | 1 | ALA4411271 | cell-based format | Scientific Literature | |
5. | ALA4411935 | Functional | Antiproliferative activity against human MR49F cells assessed as inhibition of cell growth at 30 uM after 3 days followed by compound wash and measured after 6 days by CellTiter-Glo assay relative to control | Homo sapiens | 1 | ALA4411271 | cell-based format | Scientific Literature | |
6. | ALA4411945 | Functional | Antitumor activity against human MR49F cells xenografted in NSG cells assessed as tumor growth inhibition at 100 mg/kg/day, po for 14 days and measured twice weekly relative to control | Homo sapiens | 2 | ALA4411271 | organism-based format | Scientific Literature | |
7. | ALA4411956 | Functional | Antitumor activity against human MR49F cells xenografted in NSG cells assessed as tumor growth inhibition at 30 mg/kg/day, po for 14 days and measured twice weekly relative to control | Homo sapiens | 1 | ALA4411271 | organism-based format | Scientific Literature | |
8. | ALA4676547 | Functional | Antiproliferative activity against enzalutamide-resistant human MR49F cells assessed as reduction in cell viability at 10 uM supplemented with fresh medium containing compound every 3 days for 6 days in presence of AR agonist R1881 by cell-titer glo assay relative to control | Homo sapiens | 1 | ALA4673256 | cell-based format | Scientific Literature | |
9. | ALA4676548 | Functional | Antiproliferative activity against enzalutamide-resistant human MR49F cells assessed as reduction in cell viability at 0.1 uM supplemented with fresh medium containing compound every 3 days for 6 days in presence of AR agonist R1881 by cell-titer glo assay relative to control | Homo sapiens | 1 | ALA4673256 | cell-based format | Scientific Literature | |
10. | ALA4676549 | Functional | Antiproliferative activity against enzalutamide-resistant human MR49F cells assessed as reduction in cell viability supplemented with fresh medium containing compound every 3 days for 6 days in presence of AR agonist R1881 by cell-titer glo assay | Homo sapiens | 1 | ALA4673256 | cell-based format | Scientific Literature | |
11. | ALA4810303 | Functional | Antiproliferative activity against human MR49F cells assessed as reduction in R1881-induced proliferation at 10 to 30 uM incubated for 6 days followed by medium change and subsequent addition of compound by Cell-Titer-Glo assay | Homo sapiens | 2 | ALA4808211 | cell-based format | Scientific Literature | |
12. | ALA4810312 | Functional | Antitumor activity against human MR49F cells xenografted in NOD SCID NSG mouse assessed as tumor growth inhibition at 60 mg/kg/day, po measured twice weekly for 28 days relative to control | Homo sapiens | 2 | ALA4808211 | organism-based format | Scientific Literature | |
13. | ALA4828557 | Functional | Antiproliferative activity against human MR49F cells incubated for 72 hrs by prestoblue cell viability assay | Homo sapiens | 1 | ALA4825767 | cell-based format | Scientific Literature | |
14. | ALA5140988 | Functional | Antiproliferative activity against human MR49F cells measured after 3 days by Cell Titer Glo assay | Homo sapiens | 2 | ALA5137058 | cell-based format | Scientific Literature | |
15. | ALA5140998 | Functional | Antiproliferative activity against human MR49F cells | Homo sapiens | 1 | ALA5137058 | cell-based format | Scientific Literature |