# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4414752 | Functional | Cytotoxicity against VHL-positive human RCC4/VHL cells assessed as reduction in cell viability incubated for 4 days by XTT assay | Homo sapiens | 5 | ALA4414547 | cell-based format | Scientific Literature | |
2. | ALA4414759 | Functional | Induction of DNA damage in human RCC4/VHL cells assessed as induction of p53 expression at 2.5 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
3. | ALA4414760 | Functional | Induction of DNA damage in human RCC4/VHL cells assessed as induction of p53 expression at 1.25 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
4. | ALA4414762 | Functional | Induction of autophagy in human RCC4/VHL cells assessed as increase in conversion of LC3B1 to LC3B2 expression at 2.5 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
5. | ALA4414763 | Functional | Induction of autophagy in human RCC4/VHL cells assessed as increase in conversion of LC3B1 to LC3B2 expression at 1.25 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
6. | ALA4414765 | Functional | Inhibition of autophagic flux in human RCC4/VHL cells assessed as increase in p62 expression at 2.5 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
7. | ALA4414768 | Functional | Induction of autophagy in human RCC4/VHL cells assessed as increase in LC3B1 expression incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
8. | ALA4414769 | Functional | Induction of autophagy in human RCC4/VHL cells assessed as increase in LC3B2 expression incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
9. | ALA4414771 | Functional | Inhibition of autophagic flux in human RCC4/VHL cells assessed as increase in p62 expression at 1.25 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
10. | ALA4414780 | Functional | Induction of apoptosis in human RCC4/VHL cells assessed as cleavage of pro-caspase 3 at 1.25 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
11. | ALA4414781 | Functional | Induction of apoptosis in human RCC4/VHL cells assessed as cleavage of pro-caspase 3 at 0.5 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
12. | ALA4414782 | Functional | Induction of cellular phenotype changes in human RCC4/VHL cells at 1.25 uM incubated for 24 hrs by inverted microscopic analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
13. | ALA4414783 | Functional | Induction of cellular phenotype changes in human RCC4/VHL cells at 2.5 to 10 uM incubated for 24 hrs by inverted microscopic analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
14. | ALA4830286 | Functional | Anticancer activity against human RCC4/VHL cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 reagent assay | Homo sapiens | 5 | ALA4828739 | cell-based format | Scientific Literature |