# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4422457 | F | Growth inhibition of human SK-MEL-103 cells | Homo sapiens | 8 | ALA4421731 | cell-based format | Patent Bioactivity Data | |
2. | ALA4422458 | F | Antitumor activity against human SK-MEL-103 cells xenografted in athymic nude mouse assessed as inhibition of tumor growth at 50 mg/kg, ip dosed daily | Homo sapiens | 1 | ALA4421731 | organism-based format | Patent Bioactivity Data | |
3. | ALA4422459 | F | Antitumor activity against human SK-MEL-103 cells xenografted in athymic nude mouse assessed as improvement in mouse survival at 50 mg/kg, ip dosed daily for 14 days dosed via Captisol formulation | Homo sapiens | 1 | ALA4421731 | organism-based format | Patent Bioactivity Data | |
4. | ALA4422462 | F | Antitumor activity against human SK-MEL-103 cells xenografted in athymic nude mouse assessed as improvement in mouse survival at 50 mg/kg, ip dosed daily for 4 days dosed via Captisol formulation | Homo sapiens | 1 | ALA4421731 | organism-based format | Patent Bioactivity Data | |
5. | ALA4422463 | F | Antitumor activity against human SK-MEL-103 cells xenografted in athymic nude mouse assessed as inhibition of tumor growth at 50 mg/kg, ip dosed daily for 14 days dosed via Captisol formulation relative to control | Homo sapiens | 1 | ALA4421731 | organism-based format | Patent Bioactivity Data | |
6. | ALA4422464 | F | Antitumor activity against human SK-MEL-103 cells xenografted in athymic nude mouse assessed as increase in doubling time for tumor growth at 50 mg/kg, ip dosed daily for 14 days dosed via Captisol formulation relative to control | Homo sapiens | 1 | ALA4421731 | organism-based format | Patent Bioactivity Data | |
7. | ALA4422465 | F | Antitumor activity against human SK-MEL-103 cells xenografted in athymic nude mouse assessed as growth delay time in reaching study end point (1000 mm3 tumor growth) at 50 mg/kg, ip dosed daily for 14 days dosed via Captisol formulation relative to control | Homo sapiens | 1 | ALA4421731 | organism-based format | Patent Bioactivity Data | |
8. | ALA4422466 | F | Antitumor activity against human SK-MEL-103 cells xenografted in athymic nude mouse assessed as initial tumor level at 50 mg/kg, ip dosed daily for 14 days dosed via Captisol formulation (Rvb = 80%) | Homo sapiens | 1 | ALA4421731 | organism-based format | Patent Bioactivity Data | |
9. | ALA4842685 | F | Cytotoxicity against human SK-MEL-103 cells assessed as inhibition of cell proliferation at 25 uM incubated for 72 hrs by MTT assay relative to control | Homo sapiens | 17 | ALA4842319 | cell-based format | Scientific Literature | |
10. | ALA5151562 | F | Cytotoxicity against human SK-MEL-103 cells assessed as cell growth inhibition measured after 24 hrs by WST-1 assay | Homo sapiens | 3 | ALA5149994 | cell-based format | Scientific Literature |