| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4022430 | F | Cytotoxicity against human SUM159PT cells assessed as decrease in cell viability after 120 hrs by MTS assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4029834 | F | Antiproliferative activity against human SUM159 cells up to 20 uM after 72 hrs by CellTitre-Blue assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4139917 | T | Dark toxicity against human SUM159 cells after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4139919 | F | Photocytotoxicity against human SUM159 cells assessed as growth inhibition irradiated at 420 nm at 4, 24, 48 hrs post compound addition for 5 mins measured after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA4139942 | F | Cell cycle arrest in human SUM159 cells in presence of irradiation | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA4139943 | F | Induction of reactive oxygen species generation in human SUM159 cells at 1 to 10 uM irradiated at 420 nm for 5 mins measured after 2 hrs by H2DCF-DA dye-based FACS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4185482 | F | Cytotoxicity against human SUM159PT cells assessed as cell growth inhibition after 4 days by WST-8 assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4320488 | F | Antiproliferative activity against human SUM159 cells measured after 72 hrs by MTT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 9. | ALA4320492 | F | Potency index, ratio of parthenolide IC50 to test compound IC50 for human SUM159 cells | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 10. | ALA4320498 | F | Cell cycle arrest in human SUM159 cells assessed as decrease in S-phase accumulation at 0.5 hrs measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4320499 | F | Cell cycle arrest in human SUM159 cells assessed as decrease in G2/M-phase accumulation at 0.5 hrs measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4320500 | F | Cell cycle arrest in human SUM159 cells assessed as increase in G1-phase accumulation at 0.5 hrs measured after 48 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4320501 | F | Cell cycle arrest in human SUM159 cells assessed as down regulation of CHK2 expression at 0.1 to 0.2 uM measured after 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4320503 | F | Cell cycle arrest in human SUM159 cells assessed as down regulation of CHK1 expression at 0.1 to 0.2 uM measured after 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4320506 | F | Cell cycle arrest in human SUM159 cells assessed as up regulation of P27 expression at 0.1 to 0.2 uM measured after 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4320507 | F | Induction of apoptosis in human SUM159 cells assessed as viable cells at 0.2 uM measured after 48 hrs by Annexin-V APC/propidium iodide staining based flow cytometry (Rvb = 95.9%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4320508 | F | Induction of apoptosis in human SUM159 cells assessed as early apoptotic cells at 0.2 uM measured after 48 hrs by Annexin-V APC/propidium iodide staining based flow cytometry (Rvb = 2.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4320509 | F | Induction of apoptosis in human SUM159 cells assessed as late apoptotic cells at 0.2 uM measured after 48 hrs by Annexin-V APC/propidium iodide staining based flow cytometry (Rvb = 1.45%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4320510 | F | Induction of apoptosis in human SUM159 cells assessed as necrotic cells at 0.2 uM measured after 48 hrs by Annexin-V APC/propidium iodide staining based flow cytometry (Rvb = 0.152%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4320511 | F | Induction of apoptosis in human SUM159 cells assessed as viable cells at 0.5 uM measured after 48 hrs by Annexin-V APC/propidium iodide staining based flow cytometry (Rvb = 95.9%) | Homo sapiens | 2 | cell-based format | Scientific Literature |
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