# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5249964 | F | Antiproliferative activity against human Z138 cells assessed as cell growth inhibition measured every 4 days upto 8 days by Cell Titer-Glo Luminescent Cell Viability kit method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA4013575 | F | Cytotoxicity against human Z138 cells assessed as cell growth inhibition after 12 days by Cell Titer-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4031054 | A | Prodrug activation in human Z138 cells assessed as 9-((2R,3R,4S,5R)-5-(((((2-(1H-Indol-3-yl)ethyl)amino)-(hydroxy)phosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-2-amino-7-(2-(4-chlorophenoxy)ethyl)-6-oxo-6,9-dihydro-1H-purin-7-ium formation per 5 million cells at 150 uM after 12 hrs by LC-MS/MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4031060 | A | Drug uptake in human Z138 cells assessed per 5 million cells at 150 uM after 12 hrs by LC-MS/MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA4031065 | F | Antiproliferative activity against human Z138 cells preincubated for 48 hrs followed by thymidine addition measure after 16 hrs by Thymidine incorporation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4031108 | F | Antiproliferative activity against human Z138 cells at 200 uM preincubated for 48 hrs followed by thymidine addition measure after 16 hrs by Thymidine incorporation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4130968 | F | Antiproliferative activity against human Z138 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA4192494 | F | Antiproliferative activity against human Z138 cells after 72 hrs by CellTiter Glo assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA4232659 | F | Antiproliferative activity against human Z138 cells measured after 12 days post culturing by guava via count reagent assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4232662 | F | Antitumor activity against human Z138 cells xenografted in SCID mouse assessed as tumor growth inhibition at 200 mg/kg, po BID administered for 21 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
11. | ALA4232667 | F | Antiproliferative activity against human Z138 cells after 3 days by cell titer-glo luminescent cell viability assays | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA4321377 | F | Antiproliferative activity against human Z138 cells assessed as inhibition of cell proliferation incubated for 72 hrs by Cell-titer-Glo luminescent cell viability assay | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
13. | ALA4369002 | F | Induction of apoptosis in human ibrutinib-resistant Z138 cells after 48 hrs by Annexin-V/propidium iodide staining based assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA4370773 | A | Cytostatic activity against human Z138 cells | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
15. | ALA4381269 | F | Antiproliferative activity against human Z138 cells assessed as reduction in cell viability at 10 uM incubated for 48 hrs by cell titer-glo assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA4381288 | F | Antiproliferative activity against human Z138 cells assessed as reduction in cell viability incubated for 48 hrs by cell titer-glo assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA4381323 | F | Induction of apoptosis in human Z138 cells assessed as increase in caspase-3/7 activation at 10 uM incubated for 48 hrs by luminometric caspase-glo 3/7 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA4386172 | F | Antiproliferative activity against human Z138 cells assessed as growth inhibition measured after 72 hrs by calcein AM dye-based fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA4390291 | F | Antiproliferative activity against human Z138 cells assessed as reduction in viability after 72 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
20. | ALA4390310 | F | Induction of apoptosis in human Z138 cells assessed as early apoptotic cells at 0.5 uM after 24 hrs by Annexin V-FITC/propidium iodide staining based flow cytometric analysis (Rvb = 7.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature |