# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1041517 | Functional | Induction of autophagy in VHL-null human RCC4 cells assessed as intracytoplasmic vacuoles at 5 uM after 10 days by clonogenic survival assay | Homo sapiens | 4 | ALA1154748 | cell-based format | Scientific Literature | |
2. | ALA1820683 | Functional | Induction of autophagy in human RCC4 cells assessed as formation of intracytoplasmic vacuoles at 5 uM after 24 hrs by phase contrast microscopy | Homo sapiens | 5 | ALA1817609 | cell-based format | Scientific Literature | |
3. | ALA3992746 | Functional | Growth inhibition of VHL-deficient human RCC4 cells by XTT assay | Homo sapiens | 1 | ALA3992488 | cell-based format | Scientific Literature | |
4. | ALA4050848 | Functional | Anticancer activity against human RCC4 cells after 48 hrs by XTT assay | Homo sapiens | 33 | ALA4049416 | cell-based format | Scientific Literature | |
5. | ALA4050852 | Functional | Anticancer activity against human RCC4 cells at 50 uM after 48 hrs by XTT assay | Homo sapiens | 1 | ALA4049416 | cell-based format | Scientific Literature | |
6. | ALA4050854 | Functional | Induction of apoptosis in human RCC4 cells assessed as PARP cleavage at 20 uM after 48 hrs by Western blot method | Homo sapiens | 1 | ALA4049416 | cell-based format | Scientific Literature | |
7. | ALA4050855 | Functional | Induction of autophagy in human RCC4 cells assessed as increase in LC3 lipidation at 20 uM after 48 hrs by Western blot method | Homo sapiens | 1 | ALA4049416 | cell-based format | Scientific Literature | |
8. | ALA4050856 | Functional | Induction of autophagy in human RCC4 cells assessed as increase in LC3 cleavage at 20 uM after 48 hrs by Western blot method | Homo sapiens | 1 | ALA4049416 | cell-based format | Scientific Literature | |
9. | ALA4050857 | Functional | Induction of autophagy in human RCC4 cells assessed as increase in LC3 conversion at 1 mM after 48 hrs by Western blot method | Homo sapiens | 1 | ALA4049416 | cell-based format | Scientific Literature | |
10. | ALA4414750 | Functional | Induction of autophagy in VHL-deficient human RCC4 cells assessed as increase in conversion of LC3B1 to LC3B2 expression at 2.5 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
11. | ALA4414751 | Functional | Cytotoxicity against VHL-deficient human RCC4 cells assessed as reduction in cell viability incubated for 4 days by XTT assay | Homo sapiens | 5 | ALA4414547 | cell-based format | Scientific Literature | |
12. | ALA4414756 | Functional | Induction of apoptosis in VHL-deficient human RCC4 cells assessed as cleavage of pro-caspase 3 after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
13. | ALA4414757 | Functional | Induction of DNA damage in VHL-deficient human RCC4 cells assessed as induction of p53 expression at 2.5 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
14. | ALA4414758 | Functional | Induction of DNA damage in VHL-deficient human RCC4 cells assessed as induction of p53 expression at 1.25 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
15. | ALA4414761 | Functional | Induction of autophagy in VHL-deficient human RCC4 cells assessed as increase in conversion of LC3B1 to LC3B2 expression at 1.25 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
16. | ALA4414764 | Functional | Inhibition of autophagic flux in VHL-deficient human RCC4 cells assessed as increase in p62 expression at 2.5 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
17. | ALA4414766 | Functional | Induction of autophagy in VHL-deficient human RCC4 cells assessed as increase in LC3B1 expression incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
18. | ALA4414767 | Functional | Induction of autophagy in VHL-deficient human RCC4 cells assessed as increase in LC3B2 expression incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
19. | ALA4414770 | Functional | Inhibition of autophagic flux in VHL-deficient human RCC4 cells assessed as increase in p62 expression at 1.25 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature | |
20. | ALA4414774 | Functional | Induction of apoptosis in VHL-deficient human RCC4 cells assessed as cleavage of pro-caspase 3 at 1.25 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4414547 | cell-based format | Scientific Literature |