| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4385176 | F | Protection against cisplatin-induced cytotoxicity in rat NRK-52E cells assessed as increase in cell viability at 20 uM after 24 hrs by MTT assay | Rattus norvegicus | 1 | ALA4382270 | cell-based format | Scientific Literature | |
| 2. | ALA4385177 | F | Protection against cisplatin-induced cytotoxicity in rat NRK-52E cells assessed as improvement in morphological changes after 24 hrs by microscopic analysis | Rattus norvegicus | 1 | ALA4382270 | cell-based format | Scientific Literature | |
| 3. | ALA4385178 | F | Protection against cisplatin-induced cytotoxicity in rat NRK-52E cells assessed as increase in cell viability after 24 hrs by MTT assay | Rattus norvegicus | 1 | ALA4382270 | cell-based format | Scientific Literature | |
| 4. | ALA4385179 | A | Cytotoxicity against rat NRK-52E cells assessed as effect on cell viability at 1 to 50 uM after 24 hrs by MTT assay | Rattus norvegicus | 1 | ALA4382270 | cell-based format | Scientific Literature | |
| 5. | ALA4385180 | F | Protection against cisplatin-induced cell damage in rat NRK-52E cells assessed as reduction in reactive oxygen species generation at 10 uM after 24 hrs by DCF staining based fluorescence microscopic analysis | Rattus norvegicus | 1 | ALA4382270 | cell-based format | Scientific Literature | |
| 6. | ALA4385181 | F | Protection against cisplatin-induced cell damage in rat NRK-52E cells assessed as reversal of mitochondrial membrane potential loss at 10 uM after 24 hrs by JC1 staining based fluorescence microscopic analysis | Rattus norvegicus | 1 | ALA4382270 | cell-based format | Scientific Literature | |
| 7. | ALA4385182 | F | Protection against cisplatin-induced apoptosis in rat NRK-52E cells assessed as reduction in cleaved caspase-3 level at 10 uM after 24 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA4382270 | cell-based format | Scientific Literature | |
| 8. | ALA4611852 | F | Cytoprotective activity against LPS-induced NRK-52E cells assessed as reduction in cell death measured every 5 min for 72 hrs by xCELLigence based RTCA analysis | Rattus norvegicus | 31 | ALA4610076 | cell-based format | Scientific Literature | |
| 9. | ALA4673968 | F | Antifibrotic activity in rat NRK-52E cells assessed as up regulation of TGF-beta1 inhibited E-cadherin protein expression pretreated with TGFbeta1 for 48 hrs followed by compound treatment by immunoblotting analysis | Rattus norvegicus | 1 | ALA4673208 | cell-based format | Scientific Literature | |
| 10. | ALA4673969 | F | Antifibrotic activity in rat NRK-52E cells assessed as decrease in TGFbeta1-induced alpha-SMA protein expression pretreated with TGFbeta1 for 48 hrs followed by compound treatment by immunoblotting analysis | Rattus norvegicus | 1 | ALA4673208 | cell-based format | Scientific Literature | |
| 11. | ALA4673970 | F | Antifibrotic activity in rat NRK-52E cells assessed as decrease in TGFbeta1-induced cellular morphological changes measured after 24 hrs | Rattus norvegicus | 1 | ALA4673208 | cell-based format | Scientific Literature | |
| 12. | ALA4673971 | F | Antifibrotic activity in rat NRK-52E cells assessed as decrease in TGFbeta1-induced cellular morphological changes at 24.5 mol/L measured after 24 hrs | Rattus norvegicus | 1 | ALA4673208 | cell-based format | Scientific Literature | |
| 13. | ALA4712455 | F | Cytoprotective activity in rat NRK-52E cells assessed as reduction in H/R-injury induced cell death at 300 pM incubated for 24 hrs | Rattus norvegicus | 3 | ALA4706634 | cell-based format | Scientific Literature | |
| 14. | ALA4712456 | F | Cytoprotective activity in rat NRK-52E cells assessed as reduction in cisplatin-induced cell death at 300 pM incubated for 24 hrs | Rattus norvegicus | 3 | ALA4706634 | cell-based format | Scientific Literature | |
| 15. | ALA5159811 | T | Antiproliferative activity against rat NRK-52E cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay | Rattus norvegicus | 1 | ALA5154761 | cell-based format | Scientific Literature | |
| 16. | ALA5159841 | T | Antiproliferative activity against rat NRK-52E cells at upto 10.75 uM incubated for 48 hrs by RTCA analysis | Rattus norvegicus | 1 | ALA5154761 | cell-based format | Scientific Literature | |
| 17. | ALA5241559 | T | Cytotoxicity against rat NRK-52E cells assessed as inhibition of cell growth incubated for 24 hrs by CCK-8 assay | Rattus norvegicus | 1 | ALA5241069 | cell-based format | Scientific Literature |
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