# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3869476 | F | Induction of apoptosis in mouse Panc02 cells after 72 hrs by crystal violet staining based assay | Mus musculus | 1 | ALA3868602 | cell-based format | Scientific Literature | |
2. | ALA3995326 | F | Cytotoxicity against mouse Panc02 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Mus musculus | 13 | ALA3994593 | cell-based format | Scientific Literature | |
3. | ALA4058852 | F | Antitumor activity against mouse Pan02 tumor model administered as monotherapy | Mus musculus | 1 | ALA4052817 | cell-based format | Scientific Literature | |
4. | ALA4254058 | F | Cytotoxicity against mouse Panc02 cells after 48 hrs by MTT assay | Mus musculus | 9 | ALA4251616 | cell-based format | Scientific Literature | |
5. | ALA4254067 | F | Cytotoxicity in mouse Panc02 cells assessed as reduction in cell viability at 4 uM after 48 hrs in presence of alpha-tocopherol by MTT assay | Mus musculus | 4 | ALA4251616 | cell-based format | Scientific Literature | |
6. | ALA4254070 | F | Induction of apoptosis in mouse Panc02 cells assessed as increase in caspase-3 activity at 25 uM after 5 hrs by Caspase-Glo assay | Mus musculus | 4 | ALA4251616 | cell-based format | Scientific Literature | |
7. | ALA4254074 | F | Induction of mitochondrial superoxide generation in mouse Panc02 cells at 50 uM after 2 hrs by MitoSOX red dye-based flow cytometric analysis | Mus musculus | 4 | ALA4251616 | cell-based format | Scientific Literature | |
8. | ALA4254075 | F | Induction of mitochondrial superoxide generation in mouse Panc02 cells at 50 uM after 2 hrs in presence of alpha-tocopherol by MitoSOX red dye-based flow cytometric analysis | Mus musculus | 4 | ALA4251616 | cell-based format | Scientific Literature | |
9. | ALA4254078 | F | Induction of mitochondrial ROS generation in mouse Panc02 cells at 50 uM after 2 hrs by MitoSOX red dye-based flow cytometric analysis relative to control | Mus musculus | 4 | ALA4251616 | cell-based format | Scientific Literature | |
10. | ALA4337464 | A | Cytotoxicity against mouse Panc02 cells | Mus musculus | 1 | ALA4334489 | cell-based format | Scientific Literature | |
11. | ALA4367351 | F | Antitumor activity against mouse Panc02 cells implanted in C57Bl6 mouse assessed as reduction in tumor growth at 500 mg/kg/day formulated in drinking water starting from day 7 to 25 post-tumor implantation supplemented with 1 mg bid sc dose on the weekdays and 6 mg qd ip dose on weekends by caliper method | Mus musculus | 1 | ALA4364294 | organism-based format | Scientific Literature | |
12. | ALA4367352 | F | Antitumor activity against mouse Panc02 cells implanted in C57Bl6 mouse assessed as increase in mouse survival at 500 mg/kg/day formulated in drinking water starting from day 7 to 25 post-tumor implantation supplemented with 1 mg bid sc dose on the weekdays and 6 mg qd ip dose on weekends by caliper method | Mus musculus | 1 | ALA4364294 | organism-based format | Scientific Literature | |
13. | ALA4367353 | F | Antitumor activity against mouse Panc02 cells implanted in C57Bl6 mouse assessed as reduction in tumor growth at 500 mg/kg/day formulated in drinking water starting from day 7 to 25 post-tumor implantation supplemented with 1 mg bid sc dose on the weekdays and 6 mg qd ip dose on weekends in presence of cyclophosphamide by caliper method | Mus musculus | 1 | ALA4364294 | organism-based format | Scientific Literature | |
14. | ALA4407692 | F | Antimigratory activity against mouse Panc02 cells at 1 uM after 24 hrs by wound healing assay | Mus musculus | 1 | ALA4406813 | cell-based format | Scientific Literature | |
15. | ALA4407697 | F | Inhibition of colony formation in mouse Panc02 cells after 10 days by crystal violet staining based assay | Mus musculus | 1 | ALA4406813 | cell-based format | Scientific Literature | |
16. | ALA4407700 | F | Antiproliferative activity against mouse Panc02 cells measured on day 5 by MTT assay | Mus musculus | 1 | ALA4406813 | cell-based format | Scientific Literature | |
17. | ALA4407710 | F | Antitumor activity against mouse Panc02 cells implanted in syngeneic C57BL/6 mouse assessed as reduction in tumor weight at 25 to 50 mg/kg, po treated twice daily for 3 weeks starting from 14 days post implantation | Mus musculus | 1 | ALA4406813 | organism-based format | Scientific Literature | |
18. | ALA4630488 | F | Antitumor activity against mouse Panc02 cells allografted in C57BL/6 mouse assessed as reduction in tumor growth at 50 mg/kg, po qd for 38 days | Mus musculus | 1 | ALA4627411 | organism-based format | Scientific Literature | |
19. | ALA4630489 | F | Antitumor activity against mouse Panc02 cells allografted in C57BL/6 mouse assessed as reduction in tumor growth at 50 mg/kg, po qd for 38 days in presence of anti-CTLA-4 | Mus musculus | 1 | ALA4627411 | organism-based format | Scientific Literature | |
20. | ALA4630490 | F | Antitumor activity against mouse Panc02 cells implanted in po dosed C57BL/6 mouse assessed as inhibition of GFP-positive Treg cell migration in to tumor micro environment administered 30 mins prior to Treg cell population addition followed by daily compound dosing for 5 days and measured on day 6 by flow cytometry analysis | Mus musculus | 1 | ALA4627411 | organism-based format | Scientific Literature |