| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4147732 | F | Cytotoxicity against human B-ALL cells assessed as reduction in cell viability after 24 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4335555 | F | Antiproliferative activity against mouse B-ALL cells expressing wild type BCR-ABL assessed as reduction in cell viability at 1 to 10 uM by CellTiter-Glo assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4335556 | F | Antiproliferative activity against mouse B-ALL cells harboring Bax/Bak double knockout mutant assessed as reduction in cell viability at 1 to 10 uM by CellTiter-Glo assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4335566 | F | Antiproliferative activity against mouse B-ALL cells expressing wild type BCR-ABL assessed as reduction in cell viability at 0.1 to 250 uM by CellTiter-Glo assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4335567 | F | Antiproliferative activity against mouse B-ALL cells harboring Bax/Bak double knockout mutant assessed as reduction in cell viability at 0.1 to 250 uM by CellTiter-Glo assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4335603 | F | Cytotoxicity against BCR-ABL p185-positive mouse B-ALL cells overexpressing human MCL-1 assessed as inhibition of cell viability after 24 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4335604 | F | Cytotoxicity against BCR-ABL p185-positive mouse B-ALL cells overexpressing human BCL-2 assessed as inhibition of cell viability after 24 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4335605 | F | Cytotoxicity against BCR-ABL p185- positive mouse B-ALL cells overexpressing human BCL-xL assessed as inhibition of cell viability after 24 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4335606 | F | Cytotoxicity against BCR-ABL p185-positive mouse B-ALL cells overexpressing human BFL-1 assessed as inhibition of cell viability after 24 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4335607 | F | Cytotoxicity against BCR-ABL positive p185-positive mouse B-ALL cells expressing human BCL-W assessed as inhibition of cell viability after 24 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4335608 | F | Cytotoxicity against BCR-ABL p185-positive human B-ALL cells harboring MCL-1 triple knock out mutant assessed as inhibition of cell viability after 24 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4335609 | F | Cytotoxicity against BCR-ABL p185-positive mouse B-ALL cells transfected with empty vector assessed as inhibition of cell viability after 24 hrs by AnnexinV-FITC/propidium iodide staining based flow cytometric analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4385944 | F | Antiproliferative activity against BCR-ABL positive human B-ALL cells expressing human MCl1 assessed as reduction in cell viability after 24 hrs by Annexin-V-APC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4385945 | A | Antiproliferative activity against BCR-ABL positive human B-ALL cells expressing human Bcl2 assessed as reduction in cell viability after 24 hrs by Annexin-V-APC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4385946 | A | Antiproliferative activity against BCR-ABL positive human B-ALL cells expressing human Bcl-xl assessed as reduction in cell viability after 24 hrs by Annexin-V-APC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4385947 | F | Antiproliferative activity against BCR-ABL positive human B-ALL cells expressing human BFL1 assessed as reduction in cell viability after 24 hrs by Annexin-V-APC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4385948 | F | Antiproliferative activity against BCR-ABL positive human B-ALL cells expressing human BFL-w assessed as reduction in cell viability after 24 hrs by Annexin-V-APC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4385950 | A | Antiproliferative activity against BCR-ABL-positive double bax/bak knockout human B-ALL cells assessed as reduction in cell viability after 24 hrs by Annexin-V-APC/propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4385951 | U | Selectivity ratio of IC50 for BCR-ABL positive human B-ALL cells expressing human Bcl2 to IC50 for BCR-ABL positive human B-ALL cells expressing human MCl1 | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4385952 | U | Selectivity ratio of IC50 for BCR-ABL positive human B-ALL cells expressing human Bcl-xl to IC50 for BCR-ABL positive human B-ALL cells expressing human MCl1 | Homo sapiens | 1 | cell-based format | Scientific Literature |
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