# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4324686 | F | Antitumor activity against human A375SM cells xenografted in athymic nude mice assessed as reduction in tumor volume at 100 mg/kg, po for 21 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
2. | ALA4324687 | F | Antitumor activity against human A375SM cells xenografted in athymic nude mice assessed as reduction in blood vessels formation at 100 mg/kg, po for 21 days and measured on day 50 by immunohistochemistry relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
3. | ALA4426450 | F | Antiproliferative activity against human A375SM cells harboring BRAF V600E mutant measured after 96 hrs by Cell Titer-Glo assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA4426479 | F | Antitumor activity against human A375SM cells xenografted in mouse assessed as tumor growth inhibition at 25 mg/kg, po administered bid for 20 days measured after final dosage relative to vehicle treated control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
5. | ALA4426480 | F | Antitumor activity against human A375SM cells xenografted in mouse assessed as tumor regression at 50 mg/kg, po administered bid for 20 days measured after final dosage relative to vehicle treated control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
6. | ALA4426481 | F | Antitumor activity against human A375SM cells xenografted in mouse assessed as tumor regression at 100 mg/kg, po administered qd for 20 days measured after final dosage relative to vehicle treated control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
7. | ALA4426482 | F | Antitumor activity against human A375SM cells xenografted in mouse assessed as tumor regression compound administered orally for 20 days measured after final dosage relative to vehicle treated control | Homo sapiens | 1 | cell-based format | Scientific Literature |