| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4139178 | F | Antiproliferative activity against mouse CT26.WT cells after 48 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4352923 | F | Cytostatic activity against mouse CT26.WT cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA4352955 | F | Potency index, ratio of compound IC50 to Daunomycin IC50 for mouse CT26.WT cells preincubated for 24 hrs under serum free condition followed by compound washout and further incubation for 48 hrs in presence of serum by MTT assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4480803 | F | Cytotoxicity against mouse CT26.WT cells after 72 hrs by MTT assay | Mus musculus | 57 | cell-based format | Scientific Literature | ||
| 5. | ALA4480810 | F | Induction of apoptosis in mouse CT26.WT cells assessed as subdiploid DNA content at 1 uM after 72 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 1.12%) | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4480811 | F | Induction of apoptosis in mouse CT26.WT cells assessed as subdiploid DNA content at 10 uM after 72 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 1.12%) | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4480812 | F | Induction of apoptosis in mouse CT26.WT cells assessed as subdiploid DNA content at 50 uM after 72 hrs by propidium iodide staining-based flow cytometric analysis (Rvb = 1.12%) | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4480817 | F | Induction of apoptosis in mouse CT26.WT cells assessed as viable cells at 10 uM after 72 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 94.5%) | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4480818 | F | Induction of apoptosis in mouse CT26.WT cells assessed as early apoptotic cells at 10 uM after 72 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 1.13%) | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4480819 | F | Induction of apoptosis in mouse CT26.WT cells assessed as late apoptotic cells at 10 uM after 72 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 3.92%) | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4480820 | F | Induction of apoptosis in mouse CT26.WT cells assessed as necrotic cells at 10 uM after 72 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.47%) | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5141428 | F | Antiproliferative activity against mouse CT26.WT cells assessed as reduction in cell proliferation incubated for 48 hrs by MTT assay | Mus musculus | 25 | cell-based format | Scientific Literature | ||
| 13. | ALA5141472 | F | Antiproliferative activity against mouse CT26.WT cells assessed as cell viability at 1.23 uM for 48 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5141473 | F | Antiproliferative activity against mouse CT26.WT cells assessed as cell viability at 1.11 uM for 48 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5141500 | F | Anti-tumor activity against mouse CT26.WT xenografted in BALB/c mouse assessed as decrease in tumor size at 100 mg/kg, ip twice daily and measured upto 14 days relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA5141501 | F | Anti-tumor activity against mouse CT26.WT xenografted in BALB/c mouse assessed as decrease in tumor weight at 100 mg/kg, ip twice daily and measured upto 14 days relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA5141508 | F | Anti-tumor activity against mouse CT26.WT xenografted in BALB/c mouse assessed as increase in apoptosis at 100 mg/kg, ip twice daily and measured after 14 days by TUNEL staining based assay | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA5141509 | F | Anti-tumor activity against mouse CT26.WT xenografted in BALB/c mouse assessed as increase in cleaved caspase-3 expression level at 100 mg/kg, ip twice daily and measured after 14 days by immunohistochemical analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA5141510 | F | Anti-tumor activity against mouse CT26.WT xenografted in BALB/c mouse assessed as decrease in COX-2 expression level in tumor tissue at 100 mg/kg, ip twice daily and measured after 14 days by immunohistochemical analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA5141511 | F | Anti-tumor activity against mouse CT26.WT xenografted in BALB/c mouse assessed as decrease in MMP-9 expression level in tumor tissue at 100 mg/kg, ip twice daily and measured after 14 days by immunohistochemical analysis | Mus musculus | 1 | organism-based format | Scientific Literature |
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