# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4415201 | F | Antiproliferative activity against human KYSE-30 cells assessed as cell growth inhibition at 110 uM by MTT assay relative to control | Homo sapiens | 4 | ALA4414556 | cell-based format | Scientific Literature | |
2. | ALA4415202 | F | Antiproliferative activity against human KYSE-30 cells assessed as cell growth inhibition at 55 uM by MTT assay relative to control | Homo sapiens | 1 | ALA4414556 | cell-based format | Scientific Literature | |
3. | ALA4415203 | F | Antiproliferative activity against human KYSE-30 cells assessed as cell growth inhibition at 22 uM by MTT assay relative to control | Homo sapiens | 1 | ALA4414556 | cell-based format | Scientific Literature | |
4. | ALA4415204 | F | Antiproliferative activity against human KYSE-30 cells assessed as cell growth inhibition at 450 nM by MTT assay relative to control | Homo sapiens | 1 | ALA4414556 | cell-based format | Scientific Literature | |
5. | ALA4813030 | F | Antiproliferative activity against human KYSE-30 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK8 assay | Homo sapiens | 17 | ALA4811276 | cell-based format | Scientific Literature | |
6. | ALA4822768 | F | Antiproliferative activity against human KYSE-30 cells incubated for 48 hrs by CCK8 assay | Homo sapiens | 17 | ALA4819128 | cell-based format | Scientific Literature | |
7. | ALA5044260 | F | Induction of mitochondrial membrane potential loss in human KYSE-30 cells assessed as upregulation of NOXA protein at 80 to 100 nM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
8. | ALA5044269 | F | Antiproliferative activity against human KYSE-30 cells assessed as cell viability measured after 48 hrs by CCK8 assay | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
9. | ALA5044271 | F | Antiproliferative activity against human KYSE-30 cells assessed as inhibition of colony formation at 40 to 60 nM for 7 days by crystal violet staining based analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
10. | ALA5044273 | F | Induction of cell cycle arrest in human KYSE-30 cells assessed as accumulation at G2/M phase at 100 nM measured after 48 hrs by flow cytometry analysis (Rvb = 19.38 %) | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
11. | ALA5044283 | F | Induction of apoptosis in human KYSE-30 cells assessed as apoptotic cells at 80 nM measured after 48 hrs by annexin-V-FITC and PI staining based flow cytometry analysis (Rvb = 8.1667 %) | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
12. | ALA5044285 | F | Induction of apoptosis in human KYSE-30 cells assessed as apoptotic cells at 100 nM measured after 48 hrs by annexin-V-FITC and PI staining based flow cytometry analysis (Rvb = 8.1667 %) | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
13. | ALA5044287 | F | Induction of apoptosis in human KYSE-30 cells assessed as caspase-3 cleavage at 80 to 100 nM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
14. | ALA5044288 | F | Induction of mitochondrial membrane potential loss in human KYSE-30 cells assessed as upregulation of Bax protein at 80 to 100 nM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
15. | ALA5044291 | F | Induction of mitochondrial membrane potential loss in human KYSE-30 cells assessed as downregulation of Bcl-2 protein at 80 to 100 nM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
16. | ALA5044293 | F | Induction of mitochondrial membrane potential loss in human KYSE-30 cells assessed as decrease in XIAP level at 80 to 100 nM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
17. | ALA5044295 | F | Induction of mitochondrial membrane potential loss in human KYSE-30 cells assessed as Bak expression at 80 to 100 nM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
18. | ALA5044297 | F | Induction of mitochondrial membrane potential loss in human KYSE-30 cells assessed as Bcl-xL expression at 80 to 100 nM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
19. | ALA5044299 | F | Induction of mitochondrial membrane potential loss in human KYSE-30 cells assessed as Mcl-1 expression at 80 to 100 nM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
20. | ALA5044303 | F | Antiproliferative activity against human KYSE-30 cells assessed as cell viability measured up to 48 hrs by CCK8 assay | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature |