| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA807606 | F | Rate of phosphorylation of labeled sphingosine derivative by human SPHK-1 expressed in HEK293 cells relative to rate of D-sphingosine | 8 | cell-based format | Scientific Literature | |||
| 2. | ALA864526 | B | Rate of phosphorylation by recombinant human SPHK1 | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 3. | ALA902398 | B | Effect on rate of phosphorylation of human recombinant SPHK1 expressed in HEK293 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA952612 | B | Inhibition of Sphk1 expressed in HEK293 cells | 1 | cell-based format | Scientific Literature | |||
| 5. | ALA995442 | B | Inhibition of EGFP-fused human SPHK1 expressed in CHO cells at 10 uM | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 6. | ALA995444 | B | Inhibition of EGFP-fused human SPHK1 expressed in CHO cells using D-erythro-sphingosine as substrate by Michaelis-Menten plot | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA995446 | B | Inhibition of EGFP-fused human SPHK1 expressed in CHO cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA995447 | B | Effect on EGFP-fused human SPHK1 activity expressed in CHO cells at 10 uM relative to basal level | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 9. | ALA995451 | B | Inhibition of human SPHK1 expressed in human U937 cells assessed as inhibition of endogenous sphingosine-1-phosphate levels at 5 uM after 2 hrs by ELISA | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA1032133 | B | Inhibition of SphK1 | 8 | single protein format | Scientific Literature | |||
| 11. | ALA1051862 | B | Activity at human SPHK1 at 100 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA1052796 | B | Inhibition of human sphingosine kinase 1 by off chip mobility shift assay | Homo sapiens | 27 | single protein format | Scientific Literature | ||
| 13. | ALA1105940 | B | Inhibition of SPHK1 at 5 uM | 1 | single protein format | Scientific Literature | |||
| 14. | ALA1111694 | B | Inhibition of human recombinant SPHK1 expressed in baculovirus-infected Sf9 cells in presence of sphingosine | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 15. | ALA1111705 | B | Ratio of Kinact to Km for human recombinant SPHK1 expressed in baculovirus-infected Sf9 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 16. | ALA1211760 | B | Inhibition of sphingosine kinase 1 | 29 | single protein format | Scientific Literature | |||
| 17. | ALA1246451 | B | Inhibition of Sphingosine kinase 1 in human HeLa cells at 1.25 uM pre-incubated for 24 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA1246452 | B | Inhibition of Sphingosine kinase 1 in human HeLa cells at >=5 uM pre-incubated for 24 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA1291274 | B | Non-competitive inhibition of recombinant sphingosine kinase 1 using ATP as substrate by Lineweaver-Burke plot analysis | 1 | single protein format | Scientific Literature | |||
| 20. | ALA1291277 | B | Inhibition of sphingosine kinase 1 in human A549 cells assessed as reduction in sphingosine-1-phosphate cellular level at 1 uM after 48 hrs by thin layer chromatography relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature |
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