# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4420451 | B | Inhibition of C-Myc/DDK-tagged human recombinant SYNJ2 expressed in HEK293T cells assessed as reduction in 5'-phosphatase activity incubated for 8 mins using fluorescently-labeled PI(3,4)P2 probe and Tapp1 PH-domain as detector protein by fluorescence polarization competitive assay | Homo sapiens | 24 | ALA4420065 | cell-based format | Patent Bioactivity Data | |
2. | ALA4420453 | B | Binding affinity to C-Myc/DDK-tagged human recombinant SYNJ2 expressed in HEK293T cells by microscale thermophoresis assay | Homo sapiens | 1 | ALA4420065 | cell-based format | Patent Bioactivity Data | |
3. | ALA4420460 | B | Inhibition of SYNJ2 in human MDA-MB-231 cells assessed as induction of EGFR localization within cells at 0.78 uM by immunoblot analysis | Homo sapiens | 1 | ALA4420065 | cell-based format | Patent Bioactivity Data | |
4. | ALA4421074 | B | Inhibition of C-Myc/DDK-tagged human recombinant SYNJ2 expressed in HEK293T cells assessed as reduction in 5'-phosphatase activity incubated for 8 mins using fluorescently-labeled PI(3,4)P2 probe and Tapp1 PH-domain as detector protein by fluorescence polarization competitive assay | Homo sapiens | 24 | ALA4420077 | cell-based format | Patent Bioactivity Data | |
5. | ALA4421076 | B | Binding affinity to C-Myc/DDK-tagged human recombinant SYNJ2 expressed in HEK293T cells by microscale thermophoresis assay | Homo sapiens | 1 | ALA4420077 | cell-based format | Patent Bioactivity Data | |
6. | ALA4421083 | B | Inhibition of SYNJ2 in human MDA-MB-231 cells assessed as induction of EGFR localization within cells at 0.78 uM by immunoblot analysis | Homo sapiens | 1 | ALA4420077 | cell-based format | Patent Bioactivity Data | |
7. | ALA4476942 | B | Inhibition of recombinant full length C-Myc/DDK-tagged human SYNJ2 expressed in HEK293T cells using PI(3,4,5)P3 as substrate incubated for 8 mins assessed as hydrolysis of PI(3,4,5)P3 to PI(3,4)P2 by fluorescence polarization assay | Homo sapiens | 24 | ALA4476869 | cell-based format | Patent Bioactivity Data |