# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4419311 | B | Inhibition of KLF10 in mouse CD4+CD25- T cells assessed as reduction in Foxp3 mRNA expression at 50 uM incubated for 5 days by real time qPCR analysis relative to control | Mus musculus | 3 | cell-based format | Patent Bioactivity Data | ||
2. | ALA4419314 | B | Inhibition of KLF10 in mouse CD4+CD25- T cells assessed as reduction in PD1 mRNA expression at 50 uM incubated for 5 days by real time qPCR analysis relative to control | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
3. | ALA4419315 | B | Inhibition of KLF10 in mouse CD4+CD25- T cells assessed as reduction in Foxp3 mRNA expression incubated for 5 days by real time qPCR analysis relative to control | Mus musculus | 3 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4419316 | B | Inhibition of KLF10 in mouse CD4+CD25- T cells assessed as reduction in checkpoint markers on iTregs by measuring PD1 expression level (Rvb = 87.4%) | Mus musculus | 2 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4419317 | B | Inhibition of KLF10 in mouse CD4+CD25- T cells assessed as reduction in checkpoint markers on iTregs by measuring PDL1 expression level (Rvb = 74.8%) | Mus musculus | 2 | cell-based format | Patent Bioactivity Data | ||
6. | ALA4419318 | B | Inhibition of KLF10 in mouse CD4+CD25- T cells assessed as reduction in checkpoint markers on iTregs by measuring CTLA4 expression level (Rvb = 95.9%) | Mus musculus | 2 | cell-based format | Patent Bioactivity Data |