# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA714669 | Functional | Activity tested at cloned rat Metabotropic glutamate receptor 4 expressed in Chinese Hamster Ovary (CHO) cells | 3 | ALA1144895 | cell-based format | Scientific Literature | ||
2. | ALA714670 | Binding | Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4 | 8 | ALA1135783 | single protein format | Scientific Literature | ||
3. | ALA714671 | Binding | Concentration for half maximal activation of metabotropic glutamate mGluR4a in rat | Rattus norvegicus | 7 | ALA1128305 | assay format | Scientific Literature | |
4. | ALA714672 | Binding | Effect on Metabotropic glutamate receptor 4 | 6 | ALA1130227 | single protein format | Scientific Literature | ||
5. | ALA714821 | Binding | Effective concentration against Metabotropic glutamate receptor 4 | 1 | ALA1133058 | single protein format | Scientific Literature | ||
6. | ALA714495 | Binding | Effective concentration against rat Metabotropic glutamate receptor 4 | 1 | ALA1133058 | single protein format | Scientific Literature | ||
7. | ALA714496 | Functional | Metabotropic glutamate receptor 4 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cells | 6 | ALA1148386 | cell-based format | Scientific Literature | ||
8. | ALA714497 | Functional | Metabotropic glutamate receptor 4 agonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cells; Not tested | 5 | ALA1148386 | cell-based format | Scientific Literature | ||
9. | ALA713998 | Functional | Metabotropic glutamate receptor 4 antagonist activity to influence forskolin stimulated c-AMP formation in rat non neuronal cells | 1 | ALA1148386 | cell-based format | Scientific Literature | ||
10. | ALA713999 | Binding | Inhibitory constant against cloned rat Metabotropic glutamate receptor 4 expressed in Chinese Hamster Ovary (CHO) cells | 1 | ALA1144895 | cell-based format | Scientific Literature | ||
11. | ALA714000 | Binding | Inhibitory constant against cloned rat Metabotropic glutamate receptor 4 expressed in Chinese Hamster Ovary (CHO) cells | 1 | ALA1144895 | cell-based format | Scientific Literature | ||
12. | ALA714001 | Binding | The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems. | 9 | ALA1135727 | single protein format | Scientific Literature | ||
13. | ALA714002 | Functional | Tested for inhibition of response to 30 uM of Glu at cloned rat Metabotropic glutamate receptor 4 expressed in Chinese Hamster Ovary (CHO) cells at 1 mM of the compound | 1 | ALA1144895 | cell-based format | Scientific Literature | ||
14. | ALA715718 | Functional | Antagonistic activity against rat (mGluR) metabotropic glutamate receptor 4a stably expressed in chinese hamster ovary (CHO) cells | 2 | ALA1130758 | cell-based format | Scientific Literature | ||
15. | ALA1034751 | Binding | Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium flux | Rattus norvegicus | 17 | ALA1158444 | cell-based format | Scientific Literature | |
16. | ALA1034758 | Binding | Activity at rat mGluR4 receptor expressed in HEK293 cells assessed as effect on thallium flux relative to glutamate | Rattus norvegicus | 14 | ALA1158444 | cell-based format | Scientific Literature | |
17. | ALA1034760 | Binding | Activity at rat mGluR4 expressed in HEK293 cells coexpressing Gqi5 protein assessed as fold shifting of glutamate-induced response to left at 30 uM | Rattus norvegicus | 17 | ALA1158444 | cell-based format | Scientific Literature | |
18. | ALA818780 | Binding | Compound was tested for agonistic or antagonistic activity on rat mGluR4 using the GTP-gamma 35S binding model up to 100 uM; IA means devoid of activity | 1 | ALA1132130 | single protein format | Scientific Literature | ||
19. | ALA818781 | Functional | Tested for inhibition of response to 30 uM of Glu at cloned rat mGluR4 receptor expressed in Chinese Hamster Ovary (CHO) cells at 1 mM of the compound | 1 | ALA1144895 | cell-based format | Scientific Literature | ||
20. | ALA818789 | Binding | Compound was tested in vitro for binding affinity against mGluR4a metabotropic glutamate receptor, using [3H]L-AP4 as the radioligand. | 1 | ALA1153651 | single protein format | Scientific Literature |