# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4326680 | B | Inhibition of MyD88 in ICR mouse primary peritoneal macrophages assessed as reduction in LPS-induced JNK phosphorylation at 20 uM preincubated for 30 mins followed by LPS-stimulation and measured after 20 mins by Western blot analysis | Mus musculus | 2 | ALA4325844 | single protein format | Scientific Literature | |
2. | ALA4326681 | B | Inhibition of MyD88 in ICR mouse primary peritoneal macrophages assessed as reduction in LPS-induced ERK phosphorylation at 20 uM preincubated for 30 mins followed by LPS-stimulation and measured after 20 mins by Western blot analysis | Mus musculus | 2 | ALA4325844 | single protein format | Scientific Literature | |
3. | ALA4326682 | B | Inhibition of MyD88 in ICR mouse primary peritoneal macrophages assessed as reduction in LPS-induced p38 MAPK phosphorylation at 20 uM preincubated for 30 mins followed by LPS-stimulation and measured after 20 mins by Western blot analysis | Mus musculus | 2 | ALA4325844 | single protein format | Scientific Literature | |
4. | ALA4326683 | B | Inhibition of MyD88 in ICR mouse primary peritoneal macrophages assessed as reduction in LPS-induced IkappaB levels at 20 uM preincubated for 30 mins followed by LPS-stimulation and measured after 20 mins by Western blot analysis | Mus musculus | 1 | ALA4325844 | single protein format | Scientific Literature | |
5. | ALA4326684 | B | Inhibition of MyD88 in ICR mouse primary peritoneal macrophages assessed as reduction in LPS-induced NFkappaB translocation at 20 uM preincubated for 30 mins followed by LPS-stimulation and measured after 20 mins by immunofluorescence microscopic analysis | Mus musculus | 1 | ALA4325844 | single protein format | Scientific Literature | |
6. | ALA4326685 | B | Inhibition of MyD88 in mouse RAW264.7 cells expressing EGFP-fused NFkappaB at 10 uM preincubated for 30 mins followed by LPS-stimulation and measured after 1 hr by fluorescence assay | Mus musculus | 1 | ALA4325844 | cell-based format | Scientific Literature | |
7. | ALA5166998 | B | Inhibition of MyD88 expression in R848-stimulated mouse BMDC cells at 1 to 4 uM treated for 2 hrs followed by R848 stimulation for 12 hrs by western blot analysis | Mus musculus | 1 | ALA5154907 | cell-based format | Scientific Literature |