# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA822801 | B | Inhibition of mouse c-Src tyrosine kinase | 29 | ALA1131615 | single protein format | Scientific Literature | ||
2. | ALA946593 | B | Reversal of increase in Src kinase phosphorylation in mouse MC3T3-E1 cells at 1 uM in presence of PP2 | Mus musculus | 1 | ALA1156469 | cell-based format | Scientific Literature | |
3. | ALA946594 | B | Reversal of increase in Src kinase phosphorylation in mouse MC3T3-E1 cells transfected with dominant-negative mutant Src expression vector at 1 uM | Mus musculus | 1 | ALA1156469 | cell-based format | Scientific Literature | |
4. | ALA946595 | B | Increase in Src kinase phosphorylation in mouse MC3T3-E1 cells at 1 uM | Mus musculus | 1 | ALA1156469 | cell-based format | Scientific Literature | |
5. | ALA1657368 | B | Inhibition of constitutive SRC phosphorylation in v-Src transformed mouse NIH/3T3 cells at 40 or 50 uM after 12 to 48 hrs by immunoblotting | Mus musculus | 4 | ALA1649103 | cell-based format | Scientific Literature | |
6. | ALA1657522 | B | Inhibition of EGF-srimulated SRC phosphorylation in mouse NIH/3T3 cells overexpressing human EGFR at 40 uM after 15 to 60 mins by immunoblotting | Mus musculus | 2 | ALA1649103 | cell-based format | Scientific Literature | |
7. | ALA2039192 | B | Inhibition of Tel-fused SRC in mouse BA/F3 cells | Mus musculus | 6 | ALA2034853 | cell-based format | Scientific Literature | |
8. | ALA2411060 | B | Inhibition of c-SRC phosphorylation at Y416 in mouse 32D cells expressing BCR/ABL fusion protein p210 at 1 uM by Western blotting analysis | Mus musculus | 4 | ALA2407017 | cell-based format | Scientific Literature | |
9. | ALA3861108 | B | Inhibition of Src in mouse BV2 cells assessed as suppression of LPS-induced NO release preincubated for 1 hr followed by LPS addition measured after 24 hrs by Griess assay | Mus musculus | 36 | ALA3860061 | cell-based format | Scientific Literature | |
10. | ALA3861156 | B | Inhibition of Src signaling pathway in mouse BV2 cells assessed as suppression of LPS-induced NO release at 0.01 M preincubated for 1 hr followed by LPS addition measured after 24 hrs relative to control by Griess assay | Mus musculus | 9 | ALA3860061 | cell-based format | Scientific Literature | |
11. | ALA3861157 | B | Inhibition of Src signaling pathway in mouse BV2 cells assessed as suppression of LPS-induced NO release at 0.1 to 100 uM preincubated for 1 hr followed by LPS addition measured after 24 hrs relative to control by Griess assay | Mus musculus | 6 | ALA3860061 | cell-based format | Scientific Literature | |
12. | ALA4195501 | B | Inhibition of LPS-induced SRC phosphorylation in mouse RAW264.7 cells preincubated for 1 hr followed by LPS stimulation for 30 mins by Western blot method | Mus musculus | 1 | ALA4190396 | cell-based format | Scientific Literature | |
13. | ALA4342555 | B | Inhibition of SRC in transformed mouse NIH3T3 cells by SDS-PAGE based immunoblot assay | Mus musculus | 1 | ALA4342402 | cell-based format | Scientific Literature | |
14. | ALA4371210 | B | Inhibition of Src autophosphorylation in mouse GL261 cells | Mus musculus | 1 | ALA4371003 | cell-based format | Scientific Literature | |
15. | ALA4807715 | F | In vivo inhibition of SRC phosphorylation in PBMC derived from human PC3 cells bearing mouse model at 5 mg/kg | Mus musculus | 1 | ALA4806967 | organism-based format | Patent Bioactivity Data | |
16. | ALA4807716 | F | In vivo inhibition of SRC phosphorylation in PBMC derived from human PC3 cells bearing mouse model at 50 mg/kg | Mus musculus | 1 | ALA4806967 | organism-based format | Patent Bioactivity Data | |
17. | ALA4807717 | F | In vivo inhibition of SRC phosphorylation in PBMC derived from human PC3 cells bearing mouse model assessed as plasma compound concentration required to inhibit 50 % phosphorylation | Mus musculus | 1 | ALA4806967 | organism-based format | Patent Bioactivity Data |