| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4482512 | Binding | Binding affinity to recombinant human IRS1 PH domain expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance assay | Homo sapiens | 22 | ALA4482310 | assay format | Patent Bioactivity Data | |
| 2. | ALA4482518 | Binding | Inhibition of HGF-induced IRS1 phosphorylation in human T47D cells assessed as pSer312 IRS1/total-IRS1 ratio level at 20 uM pre-incubated for 4 hrs before stimulation with HGF for 20 mins (Rvb = 100 +/- 0.02%) | Homo sapiens | 21 | ALA4482310 | cell-based format | Patent Bioactivity Data |
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