# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4421210 | B | Competitive binding affinity to full-length mouse SOX18 expressed in Sf9 cells assessed as reduction in SOX1 8- DNA binding using FAM-labelled Prox1 -DNA element at 1 to 1000 uM incubated for 5 mins in dark at room temperature, 10 mins at 37 degC and 30 mins at room temperature by fluorescence polarization assay | Mus musculus | 4 | cell-based format | Patent Bioactivity Data | ||
2. | ALA4421213 | B | Competitive binding affinity to full-length mouse SOX18 expressed in Sf9 cells assessed as reduction in SOX1 8- DNA binding using FAM-labelled Prox1 -DNA element incubated for 5 mins in dark at room temperature, 10 mins at 37 degC and 30 mins at room temperature by fluorescence polarization assay | Mus musculus | 12 | cell-based format | Patent Bioactivity Data | ||
3. | ALA4421215 | B | Inhibition of mouse SOX18 expressed in African green monkey COS7 cells assessed as reduction in SOX18 transcriptional activity by luciferase reporter gene assay | Mus musculus | 8 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4421217 | B | Competitive binding affinity to full-length mouse SOX18 expressed in Sf9 cells assessed as reduction in SOX1 8- DNA binding by measuring FP-bound fraction at 200 uM using FAM-labelled Prox1 -DNA element incubated for 5 mins in dark at room temperature, 10 mins at 37 degC and 30 mins at room temperature by fluorescence polarization assay relative to control | Mus musculus | 30 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4421218 | B | Competitive binding affinity to full-length mouse SOX18 expressed in Sf9 cells assessed as reduction in SOX1 8- DNA binding by measuring FP-bound fraction at 50 uM using FAM-labelled Prox1 -DNA element incubated for 5 mins in dark at room temperature, 10 mins at 37 degC and 30 mins at room temperature by fluorescence polarization assay relative to control | Mus musculus | 30 | cell-based format | Patent Bioactivity Data |