# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4321889 | B | Inhibition of GSDMD in human monocyte/macrophages assessed as inhibition of pyroptosis in presence of Cu2+ | Homo sapiens | 2 | ALA4321782 | single protein format | Scientific Literature | |
2. | ALA4321891 | B | Inhibition of GSDMD in LPS-induced human monocyte/macrophages assessed as inhibition of pyroptosis by fluorogenic liposome leakage assay | Homo sapiens | 2 | ALA4321782 | single protein format | Scientific Literature | |
3. | ALA4321893 | B | Inhibition of human GSDMD expressed in HEK293 cells assessed as inhibition of GSDMD -induced lethality | Homo sapiens | 1 | ALA4321782 | cell-based format | Scientific Literature | |
4. | ALA4621834 | B | Inhibition of N-terminal GSDMD p30 fragment-mediated pyroptotic-cell death in doxycyclin-treated human HEK293T cells assessed as cell death at 5 uM by LDH assay | Homo sapiens | 1 | ALA4619791 | cell-based format | Scientific Literature |