# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4346434 | F | Antagonist activity at recombinant human TAS2R39 transiently expressed in HEK293T co-expressing Galpha16gust44 assessed as inhibition of ranitidine-induced intracellular calcium level by measuring remaining activity at 25 uM by fluo-4AM dye based FLIPR assay relative to control | Homo sapiens | 2 | ALA4342523 | cell-based format | Scientific Literature | |
2. | ALA4418320 | F | Inhibition of human TAS2R39 expressed in HEK293 cells coexpressing G-protein at 10 mM assessed as reduction in epicatechin gallate-induced intracellular calcium release by Fluo-4-AM dye based fluorescence assay relative to control | Homo sapiens | 36 | ALA4418259 | cell-based format | Patent Bioactivity Data | |
3. | ALA4419014 | F | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R39 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | ALA4418912 | cell-based format | Patent Bioactivity Data | |
4. | ALA4419044 | F | Antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R39 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of epigallocatechin galiate-induced increase in intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 2 | ALA4418912 | cell-based format | Patent Bioactivity Data | |
5. | ALA4419225 | F | Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay | Homo sapiens | 1 | ALA4419163 | cell-based format | Patent Bioactivity Data | |
6. | ALA4419250 | F | Agonist activity at human TAS2R39 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level at 20 mM by Calcium-3 dye based fluorescence assay relative to control | Homo sapiens | 3 | ALA4419163 | cell-based format | Patent Bioactivity Data | |
7. | ALA4421751 | F | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R39 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | ALA4421717 | cell-based format | Patent Bioactivity Data | |
8. | ALA4421777 | F | Activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R39 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on epigallocatechin gallate-induced intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 2 | ALA4421717 | cell-based format | Patent Bioactivity Data |