# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4419019 | F | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R45 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | ALA4418912 | cell-based format | Patent Bioactivity Data | |
2. | ALA4419143 | F | Activity at human TAS2R45 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as threshold concentration of compound at which point receptor detects compounds by measuring calcium response by FLIPR assay | Homo sapiens | 1 | ALA4419120 | cell-based format | Patent Bioactivity Data | |
3. | ALA4419144 | F | Activity at human TAS2R45 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay | Homo sapiens | 1 | ALA4419120 | cell-based format | Patent Bioactivity Data | |
4. | ALA4419210 | F | Agonist activity at human TAS2R45 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay | Homo sapiens | 1 | ALA4419163 | cell-based format | Patent Bioactivity Data | |
5. | ALA4419235 | F | Agonist activity at human TAS2R45 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level at 20 mM by Calcium-3 dye based fluorescence assay relative to control | Homo sapiens | 3 | ALA4419163 | cell-based format | Patent Bioactivity Data | |
6. | ALA4421756 | F | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R45 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | ALA4421717 | cell-based format | Patent Bioactivity Data |