| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4419022 | F | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R48 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 2. | ALA4419147 | F | Activity at human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as threshold concentration of compound at which point receptor detects compounds by measuring calcium response by FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 3. | ALA4419148 | F | Activity at human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as effect on calcium response by FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 4. | ALA4419219 | F | Agonist activity at human TAS2R48 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 5. | ALA4419244 | F | Agonist activity at human TAS2R48 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level at 20 mM by Calcium-3 dye based fluorescence assay relative to control | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
| 6. | ALA4421759 | F | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R48 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 7. | ALA4482450 | F | Activation of full length human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as increase in calcium concentration by measuring deltaF/F0 ratio level at 80 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.178 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 8. | ALA4482451 | F | Activation of full length human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as increase in calcium concentration by measuring deltaF/F0 ratio level at 75 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.11 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 9. | ALA4482452 | F | Activation of full length human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as increase in calcium concentration by measuring deltaF/F0 ratio level at 70 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.14 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 10. | ALA4482453 | F | Activation of full length human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as increase in calcium concentration by measuring deltaF/F0 ratio level at 65 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.17 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 11. | ALA4482454 | F | Activation of full length human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as increase in calcium concentration by measuring deltaF/F0 ratio level at 60 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.16 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 12. | ALA4482455 | F | Activation of full length human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as increase in calcium concentration by measuring deltaF/F0 ratio level at 55 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.182 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 13. | ALA4482456 | F | Activation of full length human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as increase in calcium concentration by measuring deltaF/F0 ratio level at 50 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.2 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 14. | ALA4482457 | F | Activation of full length human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as increase in calcium concentration by measuring deltaF/F0 ratio level at 45 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.194 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 15. | ALA4482458 | F | Activation of full length human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as increase in calcium concentration by measuring deltaF/F0 ratio level at 40 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.204 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 16. | ALA4482459 | F | Activation of full length human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as increase in calcium concentration by measuring deltaF/F0 ratio level at 35 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.198 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 17. | ALA4482460 | F | Activation of full length human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as increase in calcium concentration by measuring deltaF/F0 ratio level at 30 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.182 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
| 18. | ALA4482461 | F | Activation of full length human TAS2R48 expressed in HEK-293T-Galpha16-gustducin44 cells assessed as increase in calcium concentration by measuring deltaF/F0 ratio level at 25 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.186 No_unit) | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data |
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