# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4406426 | A | Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector at 30 uM using Luc-BE as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 4 | ALA4402606 | cell-based format | Scientific Literature | |
2. | ALA4406433 | A | Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using Luc-BE as substrate after 10 mins in presence of NADPH by P450-glo luciferase based luminescence assay | Homo sapiens | 2 | ALA4402606 | cell-based format | Scientific Literature | |
3. | ALA4406439 | A | Inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using Luc-BE as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 2 | ALA4402606 | cell-based format | Scientific Literature | |
4. | ALA4406444 | A | Ratio of IC50 for inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using Luc-BE as substrate after 10 mins in presence of NADPH to IC50 for inhibition of CYP4F8 (unknown origin) in human HepG2 cell membranes transduced with lentiviral vector using Luc-BE as substrate preincubated with NADPH for 30 mins followed by substrate addition and measured after 10 mins by P450-glo luciferase based luminescence assay | Homo sapiens | 2 | ALA4402606 | cell-based format | Scientific Literature |