| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4416339 | A | Inhibition of human GNMT expressed in Escherichia coli at 10 uM assessed as reduction in SAH level using glycine as substrate in presence of SAM incubated for 30 mins by LC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4414609 | assay format | Scientific Literature | |
| 2. | ALA4416346 | A | Inhibition of human GNMT expressed in Escherichia coli at 1 uM assessed as reduction in SAH level using glycine as substrate in presence of SAM incubated for 30 mins by LC-MS/MS analysis relative to control | Homo sapiens | 1 | ALA4414609 | assay format | Scientific Literature | |
| 3. | ALA4836597 | A | Inhibition of N-terminal His-tagged human recombinant Glycine-N-methyltransferase (1 to 295 residues) expressed in Escherichia coli using glycine and SAM as substrate incubated for 30 mins by HTRF assay | Homo sapiens | 12 | ALA4834465 | assay format | Scientific Literature | |
| 4. | ALA5227826 | B | Induction of GNMT in human H7GPL cells assessed as fold increase in promoter-driven luciferase reporter expression at 10 uM measured after 24 hrs by luminescence assay relative to control | Homo sapiens | 29 | ALA5226313 | cell-based format | Scientific Literature | |
| 5. | ALA5227828 | B | Induction of GNMT in human H7GPL cells assessed as fold increase in promoter-driven luciferase reporter expression measured after 24 hrs by luminescence assay relative to control | Homo sapiens | 1 | ALA5226313 | cell-based format | Scientific Literature | |
| 6. | ALA5227833 | B | Induction of GNMT in human H7GPL cells assessed as fold increase in promoter-driven luciferase reporter expression at 2.5 uM measured after 24 hrs by luminescence assay relative to control | Homo sapiens | 26 | ALA5226313 | cell-based format | Scientific Literature |
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