| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4423907 | B | Inhibition of Gal4-fused TEAD2 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level up to 100 uM after 6 hrs by nanoluciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4423911 | B | Inhibition of Gal4-fused TEAD2 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level after 6 hrs by nanoluciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4670826 | B | Inhibition of CPM binding to nonacylated N-terminal His6-tagged human TEAD2 (217 to 447 residues) expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL cells preincubated for 10 mins followed by CPM addition and measured after 1 hr by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5033516 | B | Binding affinity to eGFP-fused human TEAD2 (217 to 447 residues) expressed in CHO-K1 cells by microscale thermophoresis analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA5033532 | B | Binding affinity to external surface of N-terminal His6-tagged human TEAD2 (217 to 447 residues) expressed in Escherichia coli BL21(DE3) assessed as melting temperature by Nano Differential scanning fluorometry | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA5105005 | B | Thermal stabilization of C-terminal human TEAD2 (217 to 447 residues) assessed as change in melting temperature by thermal shift assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA5105007 | B | Binding affinity to recombinant TEAD2 (unknown origin) assessed as increase in thermal stability by thermal shift assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA5149029 | B | Binding affinity to human TEAD2 (217 to 447 residues) expressed in Escherichia coli BL21 Star (DE3) by surface plasmon resonance assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 9. | ALA5149040 | B | Binding affinity to human TEAD2 (217 to 447 residues) expressed in Escherichia coli BL21 Star (DE3) assessed as change in melting temperature incubated for 2 hrs by measuring tryptophane fluorescence by Nano Differential scanning fluorometry | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 10. | ALA5149044 | B | Inhibition of pSF-CMV-P-FLAG tagged human TEAD2 palmitoylation transfected in HEK293 cells at 10 uM incubated for 6 hrs by Western blot analysis relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 11. | ALA5149049 | B | Binding affinity to human TEAD2 (217 to 447 residues) expressed in Escherichia coli BL21 Star (DE3) assessed as retention time by surface plasmon resonance assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA5149117 | B | Binding affinity to human TEAD2 (217 to 447 residues) expressed in Escherichia coli BL21 Star (DE3) assessed as change in melting temperature incubated for 2 hrs measuring scattering fluorescence by Nano Differential scanning fluorometry | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 13. | ALA5163789 | B | Displacement of FAM- labeled YAP1 peptide from TEAD2 (217 to 447 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant incubated for 1.5 hrs by fluorescence polarization-based competitive binding assay | Homo sapiens | 1 | assay format | Scientific Literature |
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