# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4344005 | B | Binding affinity to mouse STING by ITC assay | Mus musculus | 3 | ALA4342439 | single protein format | Scientific Literature | |
2. | ALA4344007 | B | Displacement of [3H]-cGAMP from mouse STING by filtration binding assay | Mus musculus | 1 | ALA4342439 | single protein format | Scientific Literature | |
3. | ALA4373760 | B | Inhibition of STING in mouse L929 cells assessed as reduction in cGAMP induce IFNbeta expression measured after 4 hrs by qRT-PCR | Mus musculus | 1 | ALA4373628 | cell-based format | Scientific Literature | |
4. | ALA4373762 | B | Competitive binding affinity to mouse C-terminal STING domain (139 to 378 residues) in presence of c-di-GMP by isothermal titration calorimetric method | Mus musculus | 1 | ALA4373628 | single protein format | Scientific Literature | |
5. | ALA4373763 | B | Binding affinity to mouse C-terminal STING domain (139 to 378 residues) by isothermal titration calorimetric method | Mus musculus | 1 | ALA4373628 | single protein format | Scientific Literature | |
6. | ALA4373770 | B | Inhibition of mouse STING by isothermal titration calorimetric method | Mus musculus | 2 | ALA4373628 | single protein format | Scientific Literature | |
7. | ALA4400375 | B | Agonist activity at STING in mouse J774 cells assessed as stimulation of IRF3 pathway measured after 20 hrs by luciferase reporter gene assay | Mus musculus | 7 | ALA4396969 | cell-based format | Scientific Literature | |
8. | ALA4719633 | B | Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for 48 hrs by luciferase reporter gene assay | Mus musculus | 13 | ALA4715794 | cell-based format | Scientific Literature | |
9. | ALA4719634 | B | Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for 48 hrs by luciferase reporter gene assay assay relative to 2',3'-cGAMP | Mus musculus | 12 | ALA4715794 | cell-based format | Scientific Literature | |
10. | ALA4733194 | B | Activation of mouse STING | Mus musculus | 1 | ALA4732051 | single protein format | Scientific Literature | |
11. | ALA4808259 | B | Activation of mouse STING expressed in RAW-Lucia ISG cells at 50 uM incubated for 24 hrs by quanti-blue SEAP reporter gene assay relative to control | Mus musculus | 25 | ALA4808161 | cell-based format | Scientific Literature | |
12. | ALA4808261 | B | Activation of mouse STING expressed in RAW-Lucia ISG cells incubated for 24 hrs by quanti-blue SEAP reporter gene assay | Mus musculus | 13 | ALA4808161 | cell-based format | Scientific Literature | |
13. | ALA5039524 | B | Agonist activity at mouse STING in THP-1 dual cells incubated for 20 hrs by luciferase reporter gene assay | Mus musculus | 3 | ALA5038585 | cell-based format | Scientific Literature | |
14. | ALA5039525 | B | Agonist activity at STING in mouse RAW264.7 cells incubated for 20 hrs by luciferase reporter gene assay | Mus musculus | 3 | ALA5038585 | cell-based format | Scientific Literature | |
15. | ALA5039534 | B | Agonist activity at mouse STING in THP-1 dual cells at 25 uM incubated for 20 hrs by luciferase reporter gene assay relative to ADU-S100 | Mus musculus | 2 | ALA5038585 | cell-based format | Scientific Literature | |
16. | ALA5039535 | B | Agonist activity at STING in mouse RAW264.7 cells at 25 uM incubated for 20 hrs by luciferase reporter gene assay relative to ADU-S100 | Mus musculus | 2 | ALA5038585 | cell-based format | Scientific Literature | |
17. | ALA5045530 | B | Agonist activity at STING in mouse RAW-Lucia ISG cells assessed as IRF reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay | Mus musculus | 16 | ALA5042542 | cell-based format | Scientific Literature | |
18. | ALA5045532 | B | Agonist activity at STING in mouse RAW-Lucia ISG-KO-STING cells assessed as IRF reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay | Mus musculus | 13 | ALA5042542 | cell-based format | Scientific Literature | |
19. | ALA5045536 | B | Displacement of fluorescein-labelled probe from wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) by time-resolved FRET-based competition binding assay | Mus musculus | 23 | ALA5042542 | single protein format | Scientific Literature | |
20. | ALA5045540 | B | Binding affinity to wild type mouse His-tagged STING cytoplasmic domain (155 to 341 residues) assessed as induction of protein dimerization incubated for 1 hr by time resolved FRET-based assay | Mus musculus | 23 | ALA5042542 | single protein format | Scientific Literature |