| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4316545 | B | Inhibition of His-tagged JMJD6 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as increase in H4 arginine 3 symmetrical dimethylation (H4R3me2s) content at 10 uM using core histone as substrate preincubated with enzyme for 10 mins followed by incubation with substrate for 1 hr by immunoblotting analysis | Homo sapiens | 5 | ALA4312042 | assay format | Scientific Literature | |
| 2. | ALA4316546 | B | Inhibition of JMJD6 in human HeLa cells assessed as decrease in cell proliferation measured after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 1 | ALA4312042 | cell-based format | Scientific Literature | |
| 3. | ALA4316547 | B | Inhibition of JMJD6 in human SMCC7721 cells assessed as decrease in cell proliferation measured after 72 hrs by CellTiter 96 AQueous one solution cell proliferation assay | Homo sapiens | 1 | ALA4312042 | cell-based format | Scientific Literature | |
| 4. | ALA4316548 | B | Inhibition of His-tagged JMJD6 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as decrease in demethylase activity by measuring release of formaldehyde using core histone as substrate preincubated with enzyme for 10 mins followed by incubation with substrate for 1 hr measured following 2 hrs incubation with ammonium acetate/acetoacetanilide by fluorescence based analysis | Homo sapiens | 1 | ALA4312042 | assay format | Scientific Literature | |
| 5. | ALA4316549 | B | Inhibition of JMJD6 in human HeLa cells assessed as increase in HSP70R469me1 level at 10 uM incubated for 6 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4312042 | cell-based format | Scientific Literature | |
| 6. | ALA4316550 | B | Inhibition of JMJD6 in human HeLa cells assessed as H4R3me2S level at 10 uM incubated for 6 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4312042 | cell-based format | Scientific Literature | |
| 7. | ALA4316556 | B | Binding affinity to immobilized His-tagged JMJD6 (unknown origin) expressed in Escherichia coli BL21 (DE3) by biacore-binding assay | Homo sapiens | 1 | ALA4312042 | assay format | Scientific Literature | |
| 8. | ALA4709789 | B | Binding affinity to JMJD6 (unknown origin) | Homo sapiens | 1 | ALA4706547 | single protein format | Scientific Literature | |
| 9. | ALA4733524 | B | Inhibition of JMJD6 (unknown origin) | Homo sapiens | 1 | ALA4732064 | single protein format | Scientific Literature | |
| 10. | ALA4836319 | B | Inhibition of JMJD6 (unknown origin) at 100 uM by Succinate-Glo assay | Homo sapiens | 1 | ALA4834445 | single protein format | Scientific Literature | |
| 11. | ALA4836320 | B | Inhibition of JMJD6 (unknown origin) by Succinate-Glo assay | Homo sapiens | 33 | ALA4834445 | single protein format | Scientific Literature | |
| 12. | ALA4836326 | B | Binding affinity to JMJD6 in human HeLa cells assessed as inhibition of temperature-dependent protein degradation by CETSA | Homo sapiens | 1 | ALA4834445 | cell-based format | Scientific Literature | |
| 13. | ALA4836327 | B | Binding affinity to JMJD6 (unknown origin) assessed as thermal stability of the protein by measuring change in melting temperature by differential scanning fluorimetry | Homo sapiens | 1 | ALA4834445 | single protein format | Scientific Literature | |
| 14. | ALA4836333 | B | Inhibition of JMJD6 (unknown origin) | Homo sapiens | 1 | ALA4834445 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!