| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA763227 | B | Minimum effective concentration required to inhibit pregnane X receptor (PXR) | 29 | single protein format | Scientific Literature | |||
| 2. | ALA877358 | F | Inhibition of pregnane X receptor mediated activation of alkaline phosphatase reporter gene at 10 uM | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 3. | ALA880930 | B | Inhibitory concentration against Pregnane X receptor | 2 | single protein format | Scientific Literature | |||
| 4. | ALA861915 | B | Effect on PXR activity | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA870189 | B | Inhibition of PXR | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA912149 | F | Transactivation of PXR by luciferase reporter gene assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 7. | ALA910705 | B | Increase in activation of human PXR expressed in HepG2 cells relative to rifampicin | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 8. | ALA912492 | B | Increase in human PXR activation expressed in CHO cells relative to rifampicin | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 9. | ALA2038333 | B | Activity at human PXR assessed as induction of CYP3A4 activity up to 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA2044585 | B | Inhibition of PXR | 6 | single protein format | Scientific Literature | |||
| 11. | ALA2049322 | B | Activation of PXR in human DPX2 cells after 24 hrs by luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA2049323 | B | Activation of PXR in human DPX2 cells after 24 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA2049324 | B | Activation of PXR in human DPX2 cells at <100 uM after 24 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA2049325 | B | Activation of PXR in human DPX2 cells at 100 uM after 24 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA2049328 | B | Activation of PXR in human DPX2 cells at 6.25 uM after 24 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA2090341 | B | Activation of PXR | 4 | single protein format | Scientific Literature | |||
| 17. | ALA1805306 | B | Transactivation of human PXR expressed in HepG2 cells after 18 hrs by luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA1804462 | B | Transactivation of PXR | 8 | single protein format | Scientific Literature | |||
| 19. | ALA1809501 | B | Agonist activity at human FLAG-tagged SXR ligand binding domain expressed in human HepG2 cells co-transfected with pGVP2-Gal4 vector assessed as induction of CYP3A4 gene expression at 5 x 10'-6 M after 48 hrs by dual-luciferase reporter gene assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 20. | ALA1803436 | F | Agonist activity at human SXR transfected in human HepG2 cells coexpressing GAL4 assessed as activation of receptor-mediated CYP3A4 gene transcription at 1 X 10'-6 M after 48 hrs by luciferase reporter gene assay | Homo sapiens | 9 | cell-based format | Scientific Literature |
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