| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA763227 | B | Minimum effective concentration required to inhibit pregnane X receptor (PXR) | 29 | single protein format | Scientific Literature | |||
| 2. | ALA877358 | F | Inhibition of pregnane X receptor mediated activation of alkaline phosphatase reporter gene at 10 uM | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 3. | ALA880930 | B | Inhibitory concentration against Pregnane X receptor | 2 | single protein format | Scientific Literature | |||
| 4. | ALA861915 | B | Effect on PXR activity | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 5. | ALA870189 | B | Inhibition of PXR | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA912149 | F | Transactivation of PXR by luciferase reporter gene assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 7. | ALA910705 | B | Increase in activation of human PXR expressed in HepG2 cells relative to rifampicin | Homo sapiens | 18 | cell-based format | Scientific Literature | ||
| 8. | ALA912492 | B | Increase in human PXR activation expressed in CHO cells relative to rifampicin | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 9. | ALA891766 | B | Displacement of [N-methyl-3H]GW0438X from human PXR | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 10. | ALA891767 | F | Antagonist activity at human PXR by transient transfection assay | Homo sapiens | 12 | assay format | Scientific Literature | ||
| 11. | ALA894398 | F | Activity at PXR by cell based assay | 1 | cell-based format | Scientific Literature | |||
| 12. | ALA901722 | B | Activation of human PXR expressed in HEK293 cells at 20 uM by GAL4 activation assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA901723 | B | Activation of human PXR expressed in HEK293 cells at 50 uM by GAL4 activation assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 14. | ALA947972 | B | Reduction of PXR activation at 10 uM relative to rifampicin | 19 | single protein format | Scientific Literature | |||
| 15. | ALA1012196 | B | Displacement of [3H]SR12813 from human PXR by scintillation proximity competition binding assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA1021908 | B | Activation of PXR at 10 uM relative to rifampicin | 8 | single protein format | Scientific Literature | |||
| 17. | ALA983061 | B | Induction of PXR transactivation in HepG2 cells | 4 | cell-based format | Scientific Literature | |||
| 18. | ALA983062 | B | Inhibition of refampicin-mediated PXR activation in HepG2 cells | 4 | cell-based format | Scientific Literature | |||
| 19. | ALA982029 | F | Agonist activity at PXR by SPA assay | 1 | assay format | Scientific Literature | |||
| 20. | ALA982035 | F | Agonist activity at PXR by SPA assay relative to GW-4064 | 1 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!