# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4338390 | A | Substrate activity at recombinant full-length mouse CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of GTP by HPLC-UV analysis | Mus musculus | 41 | ALA4334523 | assay format | Scientific Literature | |
2. | ALA4338393 | A | Substrate activity at recombinant full-length mouse CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of ATP by HPLC-UV analysis | Mus musculus | 41 | ALA4334523 | assay format | Scientific Literature | |
3. | ALA4373752 | B | Competitive binding affinity to mouse CGAS using ATP as substrate in presence of dsDNA by isothermal titration calorimetric method | Mus musculus | 1 | ALA4373628 | single protein format | Scientific Literature | |
4. | ALA4373753 | B | Competitive binding affinity to mouse CGAS using GTP as substrate in presence of dsDNA by isothermal titration calorimetric method | Mus musculus | 1 | ALA4373628 | single protein format | Scientific Literature | |
5. | ALA4373754 | B | Binding affinity to mouse CGAS in presence of dsDNA by isothermal titration calorimetric method | Mus musculus | 2 | ALA4373628 | single protein format | Scientific Literature | |
6. | ALA4373756 | B | Inhibition of full length mouse CGAS after 2 hrs by RF-MS analysis | Mus musculus | 1 | ALA4373628 | single protein format | Scientific Literature | |
7. | ALA5040022 | B | Inhibition of mouse cGAS expressed in RAW-Lucia ISG transfected with HT-DNA assessed as suppression of lipofectamine 2000:ds-DNA complex induced activation of cGAS incubated for 1 hr by Quanti-luc reagent based assay | Mus musculus | 25 | ALA5038595 | cell-based format | Scientific Literature | |
8. | ALA5040039 | B | Inhibition of mouse cGAS | Mus musculus | 4 | ALA5038595 | single protein format | Scientific Literature | |
9. | ALA5109084 | B | Inhibition of mouse cGAS | Mus musculus | 5 | ALA5107968 | single protein format | Scientific Literature |