| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4343791 | B | Displacement of [3H]PSB-1584 from GPR84 in mouse liver membranes measured after 6 hrs by scintillation counting method | Mus musculus | 1 | cell membrane format | Scientific Literature | ||
| 2. | ALA4675939 | F | Inverse agonist activity at recombinant mouse GPR84 receptor expressed in HEK293 cells co-expressing GNAO1 transcription variant 1 assessed as reduction in IP1 accumulation incubated for 30 mins by HTRF based immunoassay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4712174 | F | Agonist activity at mouse Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liquid scintillation spectroscopy | Mus musculus | 3 | cell membrane format | Scientific Literature | ||
| 4. | ALA4712176 | F | Agonist activity at GPR84 in LPS-treated mouse RAW 264.7 cell membrane assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liquid scintillation spectroscopy | Mus musculus | 2 | cell membrane format | Scientific Literature | ||
| 5. | ALA4712177 | F | Agonist activity at GPR84 in mouse bone-marrow-derived neutrophils assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liquid scintillation spectroscopy | Mus musculus | 2 | tissue-based format | Scientific Literature | ||
| 6. | ALA4712184 | F | Antagonist activity at mouse Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as reduction in ZQ-16-induced stimulation of [35S]GTPgammaS binding preincubated for 15 mins followed by ZQ-16 addition and subsequent addition of [35S]GTPgammaS measured after 60 mins by liquid scintillation spectroscopy | Mus musculus | 1 | cell membrane format | Scientific Literature | ||
| 7. | ALA4712185 | F | Antagonist activity at mouse Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as reduction in PSB-16671-induced stimulation of [35S]GTPgammaS binding preincubated for 15 mins followed by PSB-16671 addition and subsequent addition of [35S]GTPgammaS measured after 60 mins by liquid scintillation spectroscopy | Mus musculus | 1 | cell membrane format | Scientific Literature | ||
| 8. | ALA4712188 | F | Antagonist activity at GPR84 in LPS-treated mouse RAW 264.7 cell membrane assessed as reduction in ZQ-16-induced stimulation of [35S]GTPgammaS binding preincubated for 15 mins followed by ZQ-16 addition and subsequent addition of [35S]GTPgammaS measured after 60 mins by liquid scintillation spectroscopy | Mus musculus | 1 | cell membrane format | Scientific Literature | ||
| 9. | ALA4712189 | F | Antagonist activity at GPR84 in LPS-treated mouse RAW 264.7 cell membrane assessed as reduction in PSB-16671-induced stimulation of [35S]GTPgammaS binding preincubated for 15 mins followed by PSB-16671 addition and subsequent addition of [35S]GTPgammaS measured after 60 mins by liquid scintillation spectroscopy | Mus musculus | 1 | cell membrane format | Scientific Literature | ||
| 10. | ALA5159665 | F | Antagonist activity at mouse GPR84 expressed in HEK293 cells assessed as reduction in 6-OAU induced intracellular calcium response preincubated for 10 mins followed by agonist addition and measured after 1 min by calcium mobilization assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA5159667 | F | Antagonist activity at GPR84 expressed in mouse bone marrow cells assessed as reduction in 6-OAU induced migration in neutrophils incubated for 90 mins by flow cytometry | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA5159668 | F | Antagonist activity at GPR84 expressed in mouse bone marrow cells assessed as reduction in 6-OAU/3-OH-C12 induced migration in monocytes incubated for 90 mins by flow cytometry | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA5159693 | F | Antagonist activity at GPR84 expressed in mouse bone marrow cells assessed as reduction in 3-OH-C12 induced migration in neutrophils incubated for 90 mins by flow cytometry | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA5159694 | F | Antagonist activity at GPR84 expressed in mouse bone marrow cells assessed as reduction in 3-OH-C12 induced migration in monocytes incubated for 90 mins by flow cytometry | Mus musculus | 2 | cell-based format | Scientific Literature |
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