| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA804662 | B | Inhibitory activity against [125I]acetyl-LDL binding to mouse peritoneal macrophage scavenger receptor | 1 | single protein format | Scientific Literature | |||
| 2. | ALA804663 | B | Activity against acetyl-LDLbinding to scavenger receptor as percent inhibition of incorporation of DiI-acetyl-LDL into mouse peritoneal macrophages at 10 uM | 3 | single protein format | Scientific Literature | |||
| 3. | ALA804664 | B | Activity against acetyl-LDLbinding to scavenger receptor as percent inhibition of incorporation of DiI-acetyl-LDL into mouse peritoneal macrophages at 10 uM; NT denotes not tested | 10 | single protein format | Scientific Literature | |||
| 4. | ALA806035 | F | Percent inhibition of DiI-acetyl-LDL binding to scavenger receptor of mouse peritoneal macrophages at 100 uM | Mus musculus | 13 | assay format | Scientific Literature | ||
| 5. | ALA806190 | B | Activity against acetyl-LDLbinding to scavenger receptor as percent inhibition of incorporation of DiI-acetyl-LDL into mouse peritoneal macrophages at 30 uM | 6 | single protein format | Scientific Literature | |||
| 6. | ALA807116 | B | Activity against acetyl-LDLbinding to scavenger receptor as percent inhibition of incorporation of DiI-acetyl-LDL into mouse peritoneal macrophages at 30 uM; NT denotes not tested | 7 | single protein format | Scientific Literature | |||
| 7. | ALA807117 | B | Inhibitory activity against [125I]acetyl-LDL binding to mouse peritoneal macrophage scavenger receptor at 10 uM | 1 | single protein format | Scientific Literature | |||
| 8. | ALA880919 | B | Inhibitory activity against [125I]-acetyl-LDL binding to mouse peritoneal macrophage scavenger receptor at 100 uM | 1 | single protein format | Scientific Literature | |||
| 9. | ALA807118 | B | Inhibitory activity against [125I]acetyl-LDL binding to mouse peritoneal macrophage scavenger receptor at 30 uM | 1 | single protein format | Scientific Literature | |||
| 10. | ALA3602256 | B | Inhibition of scavenger receptor A in wild type C57BL/6 mouse BMDC assessed as gp100 (25 to 33) peptide-induced T cell activation by measuring IL2 production at 20 uM after 56 hrs by ELISA | Mus musculus | 2 | single protein format | Scientific Literature | ||
| 11. | ALA3602257 | B | Inhibition of scavenger receptor A in wild type C57BL/6 mouse BMDC assessed as OVA257-264 peptide-induced T cell activation by measuring IL2 production at 10 uM after 56 hrs by ELISA | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 12. | ALA3602258 | B | Inhibition of scavenger receptor A in wild type C57BL/6 mouse BMDC assessed as OVA257-264 peptide-induced T cell activation by measuring IL2 production at 30 uM after 56 hrs by ELISA | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 13. | ALA3602261 | B | Inhibition of scavenger receptor A in mouse DC1.2 cells assessed as decrease in poly(I:C)-induced activation of IRF3 pretreated for 2 hrs before poly(I:C) stimulation measured after 3 hrs by immunoblotting | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3602262 | B | Inhibition of scavenger receptor A in mouse DC1.2 cells assessed as decrease in poly(I:C)-induced activation of STAT1 pretreated for 2 hrs before poly(I:C) stimulation measured after 3 hrs by immunoblotting | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3876411 | B | Antagonist activity at mouse recombinant SRA extracellular domain expressed in baculovirus infected Sf21 insect cells assessed as inhibition of protein-induced reduction of IL2 gene promoter activation in anti CD3/CD28 antibody activated wild type C57BL/6 mouse B3Z T-cells at 50 uM after 5 hrs by beta-galactosidase reporter gene assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA3876412 | B | Antagonist activity at SRA in RM1-OVA tumor bearing wild type C57BL/6 mouse derived CD11bpositiveLy6ChighLy6Gnegative myeloid-derived suppressive cells co-cultured with splenocytes assessed as reduction in protein-mediated inhibition of anti CD3/CD28 antibody-induced T-cell activation by measuring IL-2 secretion pretreated for 2 hrs followed by splenocytes addition measured after 56 hrs by ELISA | Mus musculus | 1 | assay format | Scientific Literature | ||
| 17. | ALA3876413 | B | Antagonist activity at SRA in RM1-OVA tumor bearing wild type C57BL/6 mouse derived CD11bpositiveLy6ChighLy6Gnegative myeloid-derived suppressive cells co-cultured with splenocytes assessed as reduction in protein-mediated inhibition of anti CD3/CD28 antibody-induced T-cell activation by measuring IL-2 secretion at 10 to 20 uM pretreated for 2 hrs followed by splenocytes addition measured after 56 hrs by ELISA | Mus musculus | 1 | assay format | Scientific Literature | ||
| 18. | ALA3876414 | B | Antagonist activity at SRA in RM1-OVA tumor bearing wild type C57BL/6 mouse derived CD11bpositiveLy6ChighLy6Gnegative myeloid-derived suppressive cells co-cultured with splenocytes assessed as reduction in protein-mediated inhibition of anti CD3/CD28 antibody-induced T-cell proliferation at 10 to 20 uM preincubated for 2 hrs followed by splenocytes addition measured after 72 hrs by [3H]-thymidine incorporation assay | Mus musculus | 3 | assay format | Scientific Literature |
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