# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4372732 | B | Inhibition of Kif18A (unknown origin) assessed as reduction in Alexa-594 labelled microtubule gliding at 30 uM measured every 2 secs for 20 secs by epifluorescence microscopic analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA4714848 | B | Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and further incubated for 15 mins and measured after 80 mins by ADP-Glo reagent based assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
3. | ALA4731348 | B | Inhibition of recombinant human His-tagged KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and measured after 15 mins by ADP-Glo kinase assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
4. | ALA4731848 | B | Inhibition of recombinant human His-tagged KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and measured after 15 mins by ADP-Glo kinase assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
5. | ALA5051143 | B | Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and further incubated for 15 mins and measured after 40 mins by ADP-Glo reagent based assay | Homo sapiens | 149 | assay format | Patent Bioactivity Data | ||
6. | ALA5051594 | B | Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and further incubated for 15 mins and measured after 40 mins by ADP-Glo reagent based assay | Homo sapiens | 175 | assay format | Patent Bioactivity Data | ||
7. | ALA5051731 | B | Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and further incubated for 15 mins and measured after 40 mins by ADP-Glo reagent based assay | Homo sapiens | 67 | assay format | Patent Bioactivity Data | ||
8. | ALA5051732 | B | Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and further incubated for 15 mins and measured after 40 mins by ADP-Glo reagent based assay | Homo sapiens | 42 | assay format | Patent Bioactivity Data | ||
9. | ALA5051733 | B | Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and further incubated for 15 mins and measured after 40 mins by ADP-Glo reagent based assay | Homo sapiens | 14 | assay format | Patent Bioactivity Data | ||
10. | ALA5052929 | B | Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and further incubated for 15 mins and measured after 40 mins by ADP-Glo reagent based assay | Homo sapiens | 198 | assay format | Patent Bioactivity Data | ||
11. | ALA5053344 | B | Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and further incubated for 15 mins and measured after 40 mins by ADP-Glo reagent based assay | Homo sapiens | 23 | assay format | Patent Bioactivity Data | ||
12. | ALA5053357 | B | Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and further incubated for 15 mins and measured after 40 mins by ADP-Glo reagent based assay | Homo sapiens | 172 | assay format | Patent Bioactivity Data | ||
13. | ALA5224086 | B | Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in Trichoplusia ni insect cells assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 30 mins followed by ATP addition and further incubated for 15 mins by ADP-Glo reagent based assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
14. | ALA5224124 | B | Binding affinity to KIF18A (unknown origin) by NMR based assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA5224125 | B | Inhibition of KIF18A ATPase activity (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature |