# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4400032 | B | Inhibition of IP6K1 (unknown origin) in presence of ATP at Km concentration by Cheng-Prusoff equation analysis | Homo sapiens | 1 | ALA4396947 | single protein format | Scientific Literature | |
2. | ALA4400035 | B | Binding affinity to IP6K1 (unknown origin) assessed as change in melting temperature by SYPRO orange dye-based assay | Homo sapiens | 4 | ALA4396947 | single protein format | Scientific Literature | |
3. | ALA4400036 | B | Binding affinity to IP6K1 (unknown origin) assessed as change in melting temperature at 1.11 uM by SYPRO orange dye based assay | Homo sapiens | 4 | ALA4396947 | single protein format | Scientific Literature | |
4. | ALA4400037 | B | Inhibition of IP6K1 (unknown origin) incubated for 30 mins using IP6 as substrate in presence of ATP by ADP-Glo reagent based luminescence assay | Homo sapiens | 29 | ALA4396947 | single protein format | Scientific Literature | |
5. | ALA5166042 | B | Inhibition of recombinant full length human IP6K1 in HCT-116 cells assessed as reduction in InsP7 level at 10 to 30 uM measured after 30 mins by toluidine blue staining based analysis | Homo sapiens | 1 | ALA5154889 | cell-based format | Scientific Literature | |
6. | ALA5166043 | B | Inhibition of N-terminal 6His-MBP-tagged recombinant human IP6K1 expressed in Escherichia coli assessed as inhibition of [3H]-InsP6 phosphorylation measured after 180 mins by HPLC analysis | Homo sapiens | 1 | ALA5154889 | assay format | Scientific Literature | |
7. | ALA5166044 | B | Inhibition of N-terminal 6His-MBP-tagged recombinant human IP6K1 expressed in Escherichia coli assessed as inorganic phosphate release using InsP6 as substrate in presence of ATP measured after 60 to 120 mins by malachite green based colorimetric - DIPP1 coupled enzyme assay | Homo sapiens | 37 | ALA5154889 | assay format | Scientific Literature | |
8. | ALA5166049 | B | Inhibition of recombinant full length human IP6K1 assessed as inorganic phosphate release measured after 30 mins by ADP-Glo Max assay | Homo sapiens | 1 | ALA5154889 | single protein format | Scientific Literature | |
9. | ALA5166051 | B | Inhibition of N-terminal 6His-MBP-tagged recombinant human IP6K1 expressed in Escherichia coli assessed as inhibition of [3H]-InsP6 phosphorylation at 10 nM measured after 180 mins by HPLC analysis | Homo sapiens | 1 | ALA5154889 | assay format | Scientific Literature |