# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4432926 | B | Binding affinity to recombinant hexa-histidine-tagged human full-length N-GLY1 catalytic domain expressed in Escherichia coli BL21 (DE3) assessed as change in melting temperature by thermal shift assay | Homo sapiens | 9 | assay format | Scientific Literature | ||
2. | ALA4432927 | B | Binding affinity to recombinant hexa-histidine-tagged human full-length N-GLY1 catalytic domain expressed in Escherichia coli BL21 (DE3) by thermal shift assay | Homo sapiens | 9 | assay format | Scientific Literature | ||
3. | ALA5053072 | B | Inhibition of NGLY1 in human HEK293T cells at 200 uM assessed as retention of N-glycans on full-length NFE2L1 measured by electrophoretic mobility shift assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
4. | ALA5053077 | B | Inhibition of NGLY1 in human UACC-257 cells at 200 uM assessed as increase in IFN-beta1 production measured after 48 hrs | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
5. | ALA5053078 | B | Inhibition of NGLY1 in human UACC-257 cells at 200 uM assessed as increase in IL-29 production measured after 48 hrs | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
6. | ALA5053079 | B | Inhibition of NGLY1 in human SK-MEL-2 cells at 200 uM assessed as increase in IFN-beta1 production measured after 48 hrs | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
7. | ALA5053080 | B | Inhibition of NGLY1 in human SK-MEL-2 cells at 200 uM assessed as increase in IL-29 production measured after 48 hrs | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
8. | ALA5053081 | B | Inhibition of NGLY1 in human HDF51 cells at 200 uM assessed as increase in IFN-beta1 production measured after 48 hrs | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
9. | ALA5053082 | B | Inhibition of NGLY1 in human HDF51 cells at 200 uM assessed as increase in IL-29 production measured after 48 hrs | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data |