# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4420050 | F | Antagonist activity at recombinant human MrgprX4 expressed in HEK293 cells assessed as blockade of bilirubin-induced inositol phosphate accumulation incubated for 1 hr at at 37 degC followed by incubation for 30 mins at room temperature before bilirubin addition by HTRF assay relative to control | Homo sapiens | 4 | cell-based format | Patent Bioactivity Data | ||
2. | ALA4420051 | F | Inverse agonist activity at recombinant human MrgprX4 expressed in HEK293 cells assessed as reduction in inositol phosphate accumulation incubated for 1 hr at at 37 degC followed by incubation for 30 mins at room temperature by HTRF assay relative to baseline | Homo sapiens | 4 | cell-based format | Patent Bioactivity Data | ||
3. | ALA4808118 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 10 pM of bilirubin by HTRF assay | Homo sapiens | 309 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4808119 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 10 uM of bilirubin by HTRF assay | Homo sapiens | 17 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4808120 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 100 uM of conjugated bilirubin by HTRF assay | Homo sapiens | 17 | cell-based format | Patent Bioactivity Data | ||
6. | ALA4808121 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 20 uM of deoxycholic acid by HTRF assay | Homo sapiens | 17 | cell-based format | Patent Bioactivity Data | ||
7. | ALA4808122 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 50 uM of urobilin by HTRF assay | Homo sapiens | 17 | cell-based format | Patent Bioactivity Data | ||
8. | ALA4808123 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 50 uM of obeticholic acid by HTRF assay | Homo sapiens | 17 | cell-based format | Patent Bioactivity Data | ||
9. | ALA4808127 | F | Antagonist activity at human MRGPRX4 expressed in HEK cells incubated in dark for 1 hr at 37 degree C and then incubated for 30 mins at room temperature in presence of 10 uM of BAR-502 by HTRF assay | Homo sapiens | 8 | cell-based format | Patent Bioactivity Data | ||
10. | ALA4808132 | F | Agonist activity at human MRGPRX4 expressed in HEK cells using preincubated compound in dark freezer condition for 24 hrs by HTRF assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
11. | ALA4808133 | F | Agonist activity at human MRGPRX4 expressed in HEK cells using preincubated compound in dark at room temperature for 24 hrs by HTRF assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
12. | ALA4808134 | F | Agonist activity at human MRGPRX4 expressed in HEK cells using preincubated compound in light at room temperature for 24 hrs by HTRF assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
13. | ALA4808135 | F | Agonist activity at human MRGPRX4 expressed in HEK cells using preincubated compound in blue light at room temperature for 24 hrs by HTRF assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
14. | ALA4883538 | B | PRESTO-Tango GPCRome screening (MRGPRX4) | 1 | single protein format | Donated Chemical Probes - SGC Frankfurt |