| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4419640 | B | Inhibition of recombinant human PNKP assessed as reduction in PNKP 3'-phosphatase activity by measuring release of inorganic phosphate using 5'-TAMRA-tagged 20-mer oligonucleotide as substrate incubated for 30 mins by fluorescence quenching based assay | Homo sapiens | 1 | single protein format | Patent Bioactivity Data | ||
| 2. | ALA4419652 | B | Inhibition of recombinant human PNKP assessed as reduction in PNKP kinase activity by measuring at 1 uM using 20-mer oligonucleotide substrate and [gama-32P]ATP incubated for 20 mins relative to control | Homo sapiens | 1 | single protein format | Patent Bioactivity Data | ||
| 3. | ALA4419653 | B | Inhibition of recombinant human PNKP assessed as reduction in PNKP kinase activity by measuring at 50 uM using 20-mer oligonucleotide substrate and [gama-32P]ATP incubated for 20 mins relative to control | Homo sapiens | 1 | single protein format | Patent Bioactivity Data | ||
| 4. | ALA4419659 | B | Inhibition of recombinant human PNKP assessed as reduction in PNKP 3'-phosphatase activity by measuring release of inorganic phosphate at 50 uM using 5'-TAMRA-tagged 20-mer oligonucleotide as substrate incubated for 30 mins by fluorescence quenching based assay | Homo sapiens | 1 | single protein format | Patent Bioactivity Data | ||
| 5. | ALA4419662 | B | Inhibition of recombinant human PNKP assessed as reduction in PNKP 3'-phosphatase activity by measuring release of inorganic phosphate using 3'-phosphorylated 20-mer oligonucleotide by malachite green and molybdate dye based colorimetric assay | Homo sapiens | 2 | single protein format | Patent Bioactivity Data | ||
| 6. | ALA4419663 | B | Inhibition of recombinant human PNKP assessed as reduction in PNKP 3'-phosphatase activity by measuring release of inorganic phosphate at 100 uM using 5'-TAMRA-tagged 20-mer oligonucleotide as substrate incubated for 30 mins by fluorescence quenching based assay | Homo sapiens | 5 | single protein format | Patent Bioactivity Data | ||
| 7. | ALA4419664 | B | Inhibition of recombinant human PNKP assessed as reduction in PNKP 3'-phosphatase activity by measuring 3'-phosphate removal from 5'-[32P]-labeled-20-mer single-stranded oligonucleotide at 0.001 to 10 uM incubated for 3 hrs by radio gel assay | Homo sapiens | 5 | single protein format | Patent Bioactivity Data |
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