| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4423908 | B | Inhibition of Gal4-fused TEAD3 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level up to 100 uM after 6 hrs by nanoluciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4423912 | B | Inhibition of Gal4-fused TEAD3 (unknown origin) interaction with YAP expressed in human HeLa cells assessed as basal transcriptional activity level after 6 hrs by nanoluciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4670827 | B | Inhibition of CPM binding to N-terminal His6-tagged human TEAD3 (216 to 434 residues) expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL cells preincubated for 10 mins followed by CPM addition and measured after 1 hr by fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5149030 | B | Binding affinity to human TEAD3 (216 to 435 residues) expressed in Escherichia coli BL21 Star (DE3) by surface plasmon resonance assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 5. | ALA5149041 | B | Binding affinity to human TEAD3 (216 to 435 residues) expressed in Escherichia coli BL21 Star (DE3) assessed as change in melting temperature incubated for 2 hrs by measuring tryptophane fluorescence by Nano Differential scanning fluorometry | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 6. | ALA5149045 | B | Inhibition of pSF-CMV-P-FLAG tagged human TEAD3 palmitoylation transfected in HEK293 cells at 10 uM incubated for 6 hrs by Western blot analysis relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA5149048 | B | Inhibition of pSF-CMV-P-FLAG tagged human TEAD3 palmitoylation transfected in HEK293 cells at 1 uM incubated for 6 hrs by Western blot analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5149051 | B | Binding affinity to human TEAD3 (216 to 435 residues) expressed in Escherichia coli BL21 Star (DE3) assessed as retention time by surface plasmon resonance assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA5149118 | B | Binding affinity to human TEAD3 (216 to 435 residues) expressed in Escherichia coli BL21 Star (DE3) assessed as change in melting temperature incubated for 2 hrs by measuring scattering fluorescence by Nano Differential scanning fluorometry | Homo sapiens | 1 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!