| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4399512 | B | Inhibition of SMS2 in MEF cells using C6-NBD-ceramide as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by HPLC analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4399522 | B | Inhibition of SMS2 in HFD-induced obese C57BL/6J mouse liver tissue lysate using NBD-ceramide as substrate assessed as reduction in DAG synthesis preincubated for 30 mins followed by substrate addition and measured after 3 hrs by HPLC analysis | Mus musculus | 1 | subcellular format | Scientific Literature | ||
| 3. | ALA4412725 | B | Inhibition of SMS2 in C57BL/6J mouse bone marrow derived macrophages assessed as increase in [3H]-cholesterol efflux after 17 hrs by liquid scintillation analysis | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 4. | ALA4412788 | B | Inhibition of SMS2 in C57BL/6J mouse bone marrow derived macrophages after 17 hrs | Mus musculus | 1 | single protein format | Scientific Literature | ||
| 5. | ALA4628267 | B | Inhibition of mouse recombinant C-terminal FLAG-tagged SMS2 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramide pre-incubated for 60 mins followed by incubation with substrate for 30 mins measured by RapidFire/MS assay | Mus musculus | 17 | assay format | Scientific Literature |
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