# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4321890 | B | Inhibition of GSDMD in mouse monocyte/macrophages assessed as inhibition of pyroptosis in presence of Cu2+ | Mus musculus | 2 | single protein format | Scientific Literature | ||
2. | ALA4321892 | B | Inhibition of GSDMD in LPS-induced mouse monocyte/macrophages assessed as inhibition of pyroptosis by fluorogenic liposome leakage assay | Mus musculus | 2 | single protein format | Scientific Literature | ||
3. | ALA4321894 | B | Inhibition of mouse GSDMD expressed in HEK293 cells assessed as inhibition of GSDMD -induced lethality | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA4621832 | B | Inhibition of GSDMD cytosol-plasma membrane translocation in LPS-primed immortalized mouse J744A.1 cells at 5 uM followed by subsequent nigericin stimulation by immunofluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA4621833 | B | Inhibition of GSDMD cytosol-plasma membrane translocation in LPS-primed C57BL/6 mouse primary BMDM at 5 uM followed by nigericin stimulation by immunofluorescence assay | Mus musculus | 1 | assay format | Scientific Literature |