# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4307477 | B | Inhibition of recombinant mouse N-terminal PDL1 (19 to 238 residues) assessed as recovery of mouse splenocyte proliferation at 100 nM by CFSE-based FACS analysis relative to control | Mus musculus | 2 | ALA4304794 | single protein format | Scientific Literature | |
2. | ALA4330217 | B | Inhibition of PDL1 in C57BL6 mouse splenocytes assessed as protection against ant-CD3/CD28-stimulated cell proliferation at 100 nM after 4 hrs by CFSE-based FACS analysis relative to control | Mus musculus | 10 | ALA4330055 | cell-based format | Scientific Literature | |
3. | ALA4330221 | B | Inhibition of mouse PDL1 in mouse splenocytes assessed as rescue of splenocyte effector function | Mus musculus | 1 | ALA4330055 | cell-based format | Scientific Literature | |
4. | ALA4670986 | B | Binding affinity to mouse PD1-L1 (19-134 residues) expressed in Escherichia coli BL21 (DE3) incubated for 1 hr by MST analysis | Mus musculus | 4 | ALA4665815 | assay format | Scientific Literature | |
5. | ALA4706070 | B | Binding affinity to mouse PD-L1 by isothermal titration calorimetric analysis | Mus musculus | 1 | ALA4699660 | single protein format | Scientific Literature | |
6. | ALA4706072 | B | Binding affinity to mouse PD-L1 by surface plasmon resonance | Mus musculus | 1 | ALA4699660 | single protein format | Scientific Literature | |
7. | ALA4706074 | B | Binding affinity to mouse PD-L1 by CD spectroscopy | Mus musculus | 1 | ALA4699660 | single protein format | Scientific Literature | |
8. | ALA4735266 | B | Binding affinity to recombinant mouse C-terminal polyHis-tagged PDL1 extracellular domain (Met1 to Thr238 residues) expressed in HEK293 cells by isothermal titration calorimetry | Mus musculus | 1 | ALA4732116 | cell-based format | Scientific Literature | |
9. | ALA4735271 | B | Binding affinity to recombinant mouse PDL1 (Met1 to Arg238 residues) expressed in HEK293 cells by SPR analysis | Mus musculus | 1 | ALA4732116 | cell-based format | Scientific Literature | |
10. | ALA4735272 | B | Binding affinity to recombinant mouse PDL1 (Met1 to Arg238 residues) expressed in HEK293 cells assessed as association rate constant by SPR analysis | Mus musculus | 1 | ALA4732116 | cell-based format | Scientific Literature | |
11. | ALA4735273 | B | Binding affinity to recombinant mouse PDL1 (Met1 to Arg238 residues) expressed in HEK293 cells assessed as dissociation rate constant by SPR analysis | Mus musculus | 1 | ALA4732116 | cell-based format | Scientific Literature | |
12. | ALA4735274 | B | Binding affinity to recombinant mouse PDL1 (Met1 to Arg238 residues) expressed in HEK293 cells assessed as activation constant at equilibrium by SPR analysis | Mus musculus | 1 | ALA4732116 | cell-based format | Scientific Literature | |
13. | ALA4836837 | B | Binding affinity to mouse PD-L1 assessed as induction of protein dimerization by 1H NMR method | Mus musculus | 1 | ALA4834474 | single protein format | Scientific Literature | |
14. | ALA5034141 | B | Binding affinity to PDL1 in mouse lewis lung carcinoma cells assessed as thermal stability at 0.1 to 100 nM at 58 degC after 12 hrs by CESTA analysis | Mus musculus | 1 | ALA5033993 | tissue-based format | Scientific Literature | |
15. | ALA5034142 | B | Binding affinity to PDL1 in mouse lewis lung carcinoma cells assessed as thermal stability at 3 nM at 43 to 70 degC after 12 hrs by CESTA analysis | Mus musculus | 1 | ALA5033993 | tissue-based format | Scientific Literature | |
16. | ALA5048962 | B | Binding affinity to mouse PD-L1 assessed as dissociation constant by micro-scale thermophoresis analysis | Mus musculus | 1 | ALA5046280 | single protein format | Scientific Literature | |
17. | ALA5233514 | B | Inhibition of PD-L1 in mouse splenocytes assessed as increase in INFgamma release | Mus musculus | 4 | ALA5233211 | cell-based format | Scientific Literature |