| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4346426 | F | Antagonist activity at recombinant human TAS2R7 transiently expressed in HEK293T co-expressing Galpha16gust44 assessed as inhibition of chloroquine-induced intracellular calcium level by measuring remaining activity at 25 uM by fluo-4AM dye based FLIPR assay relative to control | Homo sapiens | 2 | ALA4342523 | cell-based format | Scientific Literature | |
| 2. | ALA4419003 | F | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R7 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | ALA4418912 | cell-based format | Patent Bioactivity Data | |
| 3. | ALA4419029 | F | Potentiation of quinine sulfate-induced agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R7 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | ALA4418912 | cell-based format | Patent Bioactivity Data | |
| 4. | ALA4419049 | F | Antagonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R7 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as inhibition of quinine sulfate-induced increase in intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | ALA4418912 | cell-based format | Patent Bioactivity Data | |
| 5. | ALA4419206 | F | Agonist activity at human TAS2R7 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay | Homo sapiens | 1 | ALA4419163 | cell-based format | Patent Bioactivity Data | |
| 6. | ALA4419231 | F | Agonist activity at human TAS2R7 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level at 20 mM by Calcium-3 dye based fluorescence assay relative to control | Homo sapiens | 3 | ALA4419163 | cell-based format | Patent Bioactivity Data | |
| 7. | ALA4421740 | F | Agonist activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R7 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as effect on intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | ALA4421717 | cell-based format | Patent Bioactivity Data | |
| 8. | ALA4421782 | F | Activity at recombinant human N-terminal rat ST3 receptor-fused TAS2R7 expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in quinine sulfate-induced intracellular calcium level at 100 uM by FLIPR assay | Homo sapiens | 1 | ALA4421717 | cell-based format | Patent Bioactivity Data | |
| 9. | ALA4482326 | F | Agonist activity at N-terminal rat ST3 receptor-fused full length human TAS2R7 transiently expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by measuring deltaF/F0 ratio level at 1.3 mM by Fluo-4AM dye based FLIPR assay | Homo sapiens | 1 | ALA4482301 | cell-based format | Patent Bioactivity Data | |
| 10. | ALA4482327 | F | Agonist activity at N-terminal rat ST3 receptor-fused full length human TAS2R7 transiently expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by measuring deltaF/F0 ratio level at 2.60 mM by Fluo-4AM dye based FLIPR assay | Homo sapiens | 1 | ALA4482301 | cell-based format | Patent Bioactivity Data | |
| 11. | ALA4482328 | F | Agonist activity at N-terminal rat ST3 receptor-fused full length human TAS2R7 stably expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by measuring deltaF/F0 ratio level at 2.60 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.65 +/- 0.13 No_unit) | Homo sapiens | 1 | ALA4482301 | cell-based format | Patent Bioactivity Data | |
| 12. | ALA4482329 | F | Agonist activity at N-terminal rat ST3 receptor-fused full length human TAS2R7 stably expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by measuring deltaF/F0 ratio level at 0.65 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.41 +/- 0.14 No_unit) | Homo sapiens | 1 | ALA4482301 | cell-based format | Patent Bioactivity Data | |
| 13. | ALA4482330 | F | Agonist activity at N-terminal rat ST3 receptor-fused full length human TAS2R7 stably expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by measuring deltaF/F0 ratio level at 1.3 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.53 +/- 0.1 No_unit) | Homo sapiens | 1 | ALA4482301 | cell-based format | Patent Bioactivity Data | |
| 14. | ALA4482331 | F | Agonist activity at N-terminal rat ST3 receptor-fused full length human TAS2R7 stably expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by measuring deltaF/F0 ratio level at 0.33 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.34 +/- 0.06 No_unit) | Homo sapiens | 1 | ALA4482301 | cell-based format | Patent Bioactivity Data | |
| 15. | ALA4482332 | F | Agonist activity at N-terminal rat ST3 receptor-fused full length human TAS2R7 stably expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by measuring deltaF/F0 ratio level at 0.16 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.15 +/- 0.06 No_unit) | Homo sapiens | 1 | ALA4482301 | cell-based format | Patent Bioactivity Data | |
| 16. | ALA4482333 | F | Agonist activity at N-terminal rat ST3 receptor-fused full length human TAS2R7 stably expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by measuring deltaF/F0 ratio level at 0.08 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.1 +/- 0.04 No_unit) | Homo sapiens | 1 | ALA4482301 | cell-based format | Patent Bioactivity Data | |
| 17. | ALA4482334 | F | Agonist activity at N-terminal rat ST3 receptor-fused full length human TAS2R7 stably expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by measuring deltaF/F0 ratio level at 0.04 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.08 +/- 0.03 No_unit) | Homo sapiens | 1 | ALA4482301 | cell-based format | Patent Bioactivity Data | |
| 18. | ALA4482335 | F | Agonist activity at N-terminal rat ST3 receptor-fused full length human TAS2R7 stably expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by measuring deltaF/F0 ratio level at 0.02 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.08 +/- 0.03 No_unit) | Homo sapiens | 1 | ALA4482301 | cell-based format | Patent Bioactivity Data | |
| 19. | ALA4482336 | F | Agonist activity at N-terminal rat ST3 receptor-fused full length human TAS2R7 stably expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by measuring deltaF/F0 ratio level at 0.01 mM by Fluo-4AM dye based FLIPR assay (Rvb = 0.09 +/- 0.04 No_unit) | Homo sapiens | 1 | ALA4482301 | cell-based format | Patent Bioactivity Data | |
| 20. | ALA4482337 | F | Agonist activity at N-terminal rat ST3 receptor-fused full length human TAS2R7 transiently expressed in HEK293T cells co-expressing Galpha16gust44 assessed as increase in intracellular calcium level by measuring deltaF/F0 ratio level at 0.65 mM by Fluo-4AM dye based FLIPR assay | Homo sapiens | 1 | ALA4482301 | cell-based format | Patent Bioactivity Data |
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