| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4346422 | F | Antagonist activity at recombinant human TAS2R1 transiently expressed in HEK293T co-expressing Galpha16gust44 assessed as inhibition of picric acid-induced intracellular calcium level by measuring remaining activity at 25 uM by fluo-4AM dye based FLIPR assay relative to control | Homo sapiens | 2 | ALA4342523 | cell-based format | Scientific Literature | |
| 2. | ALA4346441 | B | Agonist activity at TAS2R1 (unknown origin) at 25 uM by transiently expressed cell-based assay | Homo sapiens | 1 | ALA4342523 | cell-based format | Scientific Literature | |
| 3. | ALA4346443 | B | Agonist activity at TAS2R1 (unknown origin) by stably expressed cell-based assay | Homo sapiens | 1 | ALA4342523 | cell-based format | Scientific Literature | |
| 4. | ALA4417661 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 100 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 5. | ALA4417662 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 50 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 6. | ALA4417663 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 7. | ALA4417664 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 12.5 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 8. | ALA4417665 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 6.25 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 9. | ALA4417666 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 3.125 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 10. | ALA4417667 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 1.5625 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 11. | ALA4417668 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 0.7813 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 12. | ALA4417669 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 0.3906 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 13. | ALA4417670 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 14. | ALA4417720 | F | Antagonist activity at full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as inhibition of sucralose-induced calcium flux at 25 uM by Fluo-4 dye based FLIPR assay | Homo sapiens | 2 | ALA4417621 | cell-based format | Patent Bioactivity Data | |
| 15. | ALA4418935 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 100 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4418911 | cell-based format | Patent Bioactivity Data | |
| 16. | ALA4418936 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 50 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4418911 | cell-based format | Patent Bioactivity Data | |
| 17. | ALA4418937 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 25 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4418911 | cell-based format | Patent Bioactivity Data | |
| 18. | ALA4418938 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 12.5 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4418911 | cell-based format | Patent Bioactivity Data | |
| 19. | ALA4418939 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 6.25 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4418911 | cell-based format | Patent Bioactivity Data | |
| 20. | ALA4418940 | F | Activation of full-length human TAS2R1 expressed in HEK293T/Galpha16-gustducin 44 cells assessed as effect on calcium flux by measuring deltaF/F0 ratio at 3.125 mM by Fluo-4 dye based FLIPR assay | Homo sapiens | 1 | ALA4418911 | cell-based format | Patent Bioactivity Data |
The page will load shortly, Thanks for your patience!