# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4419667 | B | Inhibition of human LARG (765 to 1138 residues) RhoGEF-catalyzed guanine nucleotide-exchange reaction of human full length RhoA (1 to 193 residues) by measuring inhibition of TR-GTP association to RhoA by BODIPY-Texas Red(TR)-GTP nucleotide based assay | Homo sapiens | 1 | ALA4419173 | single protein format | Patent Bioactivity Data | |
2. | ALA4419668 | B | Inhibition of human LARG (765 to 1138 residues) RhoGEF-catalyzed guanine nucleotide-exchange reaction of human full length RhoA (1 to 193 residues) by measuring inhibition of FL-GDP dissociation from RhoA by BODIPY-fluorescein(FL)-GDP nucleotide based assay | Homo sapiens | 1 | ALA4419173 | single protein format | Patent Bioactivity Data | |
3. | ALA4419711 | B | Inhibition of human LARG (765 to 1138 residues) RhoGEF binding to human full length RhoA (1 to 193 residues) in presence of Rhosin/G04 | Homo sapiens | 1 | ALA4419173 | single protein format | Patent Bioactivity Data | |
4. | ALA4419712 | B | Inhibition of human LARG (765 to 1138 residues) RhoGEF binding to human full length RhoA (1 to 193 residues) | Homo sapiens | 2 | ALA4419173 | single protein format | Patent Bioactivity Data | |
5. | ALA4419734 | B | Inhibition of human LARG (765 to 1138 residues) RhoGEF-catalyzed guanine nucleotide-exchange reaction of human full length RhoA (1 to 193 residues) by measuring inhibition of the GDP dissociation from RhoA by Alexa 647 fluorescence dye based GDP/GTP exchange assay | Homo sapiens | 1 | ALA4419173 | single protein format | Patent Bioactivity Data | |
6. | ALA4419735 | B | Binding affinity to recombinant human LARG (765 to 1138 residues) N983A mutant by microscale thermophoresis analysis | Homo sapiens | 1 | ALA4419173 | single protein format | Patent Bioactivity Data | |
7. | ALA4419736 | B | Binding affinity to recombinant human LARG (765 to 1138 residues) K979A mutant by microscale thermophoresis analysis | Homo sapiens | 1 | ALA4419173 | single protein format | Patent Bioactivity Data | |
8. | ALA4419737 | B | Binding affinity to recombinant human LARG (765 to 1138 residues) E982A mutant by microscale thermophoresis analysis | Homo sapiens | 1 | ALA4419173 | single protein format | Patent Bioactivity Data | |
9. | ALA4419738 | B | Binding affinity to recombinant human LARG (765 to 1138 residues) V1099A mutant by microscale thermophoresis analysis | Homo sapiens | 1 | ALA4419173 | single protein format | Patent Bioactivity Data | |
10. | ALA4419739 | B | Binding affinity to recombinant human LARG (765 to 1138 residues) containing DH-PH catalytic module by microscale thermophoresis analysis | Homo sapiens | 1 | ALA4419173 | single protein format | Patent Bioactivity Data |