# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4384934 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
2. | ALA4384935 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 10 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
3. | ALA4384936 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release at 10 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
4. | ALA4384937 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
5. | ALA4384938 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis | Rattus norvegicus | 21 | cell-based format | Scientific Literature | ||
6. | ALA4384939 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 21 | cell-based format | Scientific Literature | ||
7. | ALA4384940 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 1 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
8. | ALA4384941 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release at 1 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
9. | ALA4384942 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 10 to 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
10. | ALA4384943 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release at 10 to 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
11. | ALA4384944 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in LPS-induced creatine kinase levels at 10 to 20 uM preincubated for 1 hr followed by LPS stimulation for 5 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
12. | ALA4384945 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 20 uM preincubated for 1 hr followed by induction of hypoxia measured after 3 hrs by NADP reduction based colorimetric analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
13. | ALA4384946 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH levels by measuring NADH levels at 20 uM preincubated for 1 hr followed by induction of hypoxia measured after 3 hrs by colorimetric analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
14. | ALA4384947 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 5 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
15. | ALA4384948 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release at 5 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
16. | ALA4384949 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced creatine kinase levels at 30 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADP reduction based colorimetric analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
17. | ALA4384950 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced LDH release at 30 uM preincubated for 1 hr followed by hypoxia for 3 hrs by NADH detection based colorimetric analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
18. | ALA4384952 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced IL-1beta mRNA expression at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by RT-qPCR analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
19. | ALA4384954 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced TRAM protein expression at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by Western blot analysis relative to untreated control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
20. | ALA4384955 | B | Inhibition of TLR4 in Sprague-Dawley rat cardiomyocytes assessed as reduction in hypoxia-induced IRF3 protein expression at 20 uM preincubated for 1 hr followed by hypoxia for 3 hrs by Western blot analysis relative to untreated control | Rattus norvegicus | 1 | cell-based format | Scientific Literature |