# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4350056 | B | Inhibition of mouse PDS stably expressed in FRT cells coexpressing EYFP-H148Q/I152L/F46L assessed as reduction in I-/Cl- exchange incubated for 10 mins by fluorescence based assay | Mus musculus | 17 | cell-based format | Scientific Literature | ||
2. | ALA4375441 | B | Inhibition of mouse slc26a4 expressed in FRT cells co-expressing EYFP-H148Q/I152L/F46L assessed as reduction in protein-mediated chloride/iodide exchange at 10 uM preincubated for 10 mins followed by NaI-substituted PBS addition and measured by YFP-based fluorescence assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
3. | ALA4418158 | B | Inhibition of mouse pendrin expressed in FRT cells co-expressing YFP-HIF assessed as reduction in pendrin-mediated exchange of Cl(-) with SCN(-) by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4418159 | B | Inhibition of mouse pendrin expressed in FRT cells co-expressing YFP-HIF assessed as reduction in pendrin-mediated exchange of Cl(-) with I(-) by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4418160 | B | Inhibition of mouse pendrin expressed in FRT cells co-expressing YFP-HIF assessed as reduction in pendrin-mediated exchange of Cl(-) with NO3(-) by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
6. | ALA4418161 | B | Inhibition of mouse pendrin expressed in FRT cells co-expressing YFP-HIF assessed as reduction in pendrin-mediated kinetics of CI7HCO3(-) exchange by pH-sensitive fluorescent probe BCECF-AM based fluorescence assay relative to control | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
7. | ALA5053131 | B | Inhibition of mouse Slc26a4-mediated Cl-/ I- exchange at 10 uM measured by cell-based fluorescence assay | Mus musculus | 1 | cell-based format | Patent Bioactivity Data | ||
8. | ALA5231876 | B | Inhibition of mouse Pendrin stably expressed in FRT cells with YFP assessed as inhibition of pendrin mediated Cl-/SCN- exchange by fluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
9. | ALA5231877 | B | Inhibition of mouse Pendrin stably expressed in FRT cells with YFP assessed as inhibition of pendrin mediated Cl-/NO3- exchange by fluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
10. | ALA5231878 | B | Inhibition of mouse Pendrin stably expressed in FRT cells with YFP assessed as inhibition of pendrin mediated Cl-/HCO3- exchange by fluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature |