# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4482712 | B | Inhibition of N-terminal His-tagged human PC-TP expressed in Escherichia coli using NBD-PC and donor and acceptor small unilamellar vesicles by fluorescence quench assay | Homo sapiens | 26 | assay format | Patent Bioactivity Data | ||
2. | ALA4482713 | B | Inhibition of N-terminal His-tagged human PC-TP expressed in Escherichia coli at 100 uM using NBD-PC and donor and acceptor small unilamellar vesicles by fluorescence quench assay relative to control | Homo sapiens | 2 | assay format | Patent Bioactivity Data | ||
3. | ALA4482714 | B | Inhibition of N-terminal His-tagged human PC-TP expressed in Escherichia coli at 50 uM using NBD-PC and donor and acceptor small unilamellar vesicles by fluorescence quench assay relative to control | Homo sapiens | 2 | assay format | Patent Bioactivity Data | ||
4. | ALA4482717 | B | Inhibition of PC-TP in human hepatocytes assessed as enhancement of insulin signaling by measuring p-S6K T389 levels at 0.05 to 0.1 uM incubated for 60 mins by immunoblot analysis | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4482718 | B | Inhibition of PC-TP in human hepatocytes assessed as enhancement of insulin signaling by measuring p-AKT S473 levels at 0.05 to 0.1 uM incubated for 60 mins by immunoblot analysis | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
6. | ALA4482719 | B | Inhibition of PC-TP in human hepatocytes assessed as enhancement of insulin signaling by measuring p-GSK-3beta S9 levels at 0.05 to 0.1 uM incubated for 60 mins by immunoblot analysis | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
7. | ALA4482720 | B | Inhibition of PC-TP in human hepatocytes assessed as enhancement of insulin signaling by measuring p-AMPK-alpha T172 levels at 0.05 to 0.1 uM incubated for 60 mins by immunoblot analysis | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
8. | ALA4482721 | B | Binding affinity to N-terminal His-tagged human PC-TP expressed in Escherichia coli by SPR assay | Homo sapiens | 1 | assay format | Patent Bioactivity Data | ||
9. | ALA4482722 | B | Binding affinity to N-terminal His-tagged human PC-TP expressed in Escherichia coli at 5 to 75 uM in presence of TCNQ by fluorescent pyrene-labeled phosphatidylcholine based displacement assay | Homo sapiens | 1 | assay format | Patent Bioactivity Data | ||
10. | ALA4482723 | B | Binding affinity to N-terminal His-tagged human PC-TP expressed in Escherichia coli assessed as relative binding constant K(rel) at 5 to 75 uM in presence of TCNQ by fluorescent pyrene-labeled phosphatidylcholine based displacement assay relative to control | Homo sapiens | 1 | assay format | Patent Bioactivity Data | ||
11. | ALA4482724 | B | Binding affinity to N-terminal His-tagged human PC-TP expressed in Escherichia coli assessed as relative binding constant K(rel) by measuring K(rel)(Compound 4/PyrPC)/K(rel)(PC/PyrPC) ratio level at 5 to 75 uM in presence of TCNQ by fluorescent pyrene-labeled phosphatidylcholine based displacement assay relative to control | Homo sapiens | 1 | assay format | Patent Bioactivity Data | ||
12. | ALA4482725 | B | Inhibition of N-terminal His-tagged human PC-TP expressed in Escherichia coli at 30 uM using NBD-PC and donor and acceptor small unilamellar vesicles by fluorescence quench assay relative to control | Homo sapiens | 1 | assay format | Patent Bioactivity Data |